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ATLA 43, 365, 2015 365 rised pesticide products. Pending final approval, IIVS Training in China the new testing framework will be based on three non-animal methods (in vitro/ex vivo), which IIVS continues its work to help China reduce its can be used in place of the rabbit test to deter- reliance on animals for the registration and mine the eye irritation potential of commonly- testing of cosmetics, through the training of used household cleaning products with Chinese scientists. anti-microbial claims. In October 2015, as part of its Memorandum The EPA is also finalising the Process for Est ab - of Understanding with China’s National lishing & Implementing Alternative Approaches Institute of Food and Drug Control (NIFDC), to Traditional In Vivo Acute Toxicity Studies, IIVS scientists conducted a one-week training which was open to public comments early in course at the Zhejiang IFDC. The hands-on 2015. Several validated in vitro assays are avail- training focused on methods for eye irritation able through OECD test guidelines, and could and skin sensitisation, while lectures addressed offer alternatives for moving even further away integrated testing approaches, discussion of from the in vivo testing strategy of the ‘six-pack’ alternative endpoints for skin corrosion/irrita- approach, pending analysis of their capacity to tion, ocular irritation, skin sensitisation and address US EPA hazard categories. product stewardship. IIVS to Host April 2016 Workshop — IIVS Practical Methods in In Vitro In Vitro Exposure Systems and Toxicology Workshop Dosimetry Assessment Tools for Observation spots are still available for the IIVS Inhaled Tobacco Products 2016 Practical Methods in In Vitro Toxicology Workshop, which will take place at IIVS In support of its Respiratory Toxicology (Gaithersburg, MD, USA) on 11–14 January Program, IIVS will host a three-day workshop 2016. During this three-day programme, partic- on 4–6 April 2016 that promotes the use of in ipants will hear from experts in the in vitro tox- vitro models in testing and assessing the poten- icology field, and gain laboratory experience tial toxicity of pulmonary toxicants. Presenters and instruction through observation. For the from industry, government, academia and non- latest IIVS news and information, visit our web- profit organisations will explore topics such as: site at www.iivs.org. — tobacco smoke and e-cigarette aerosols; — air–liquid interface in vitro exposure sys- tems; — dosimetry approaches for particles and EPA Updates its Policy on an vapours; Important ‘Six-pack’ Endpoint — in vitro dosimetry determinations; and Following Collaboration with IIVS — exposure microenvironment/physiology of and Industry cells. This workshop is the third workshop of its A multi-year project between IIVS, industry and kind. The first was held in December 2014, fol- the US Environmental Protection Agency (EPA) lowed by a second one, in June 2015. For more has resulted in an updated policy for the use of information on registration, poster abstract an alternative testing framework for the classifi- submission and more, visit www.iivs.org. cation of eye irritation potential of EPA-autho-
Alternatives to Laboratory Animals – SAGE
Published: Dec 1, 2015
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