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Hookworm re-infection rate and efficacy of single-dose albendazole among pregnant women in Debre Elias District, Northwest Ethiopia: A single-arm trial

Hookworm re-infection rate and efficacy of single-dose albendazole among pregnant women in Debre... Hookworm is one of the soil-transmitted nematodes causing anaemia and low birth weight in pregnant women. This study aimed to assess albendazole efficacy and re-infection rate among pregnant women. A community-based cross-sectional study was conducted from February to September 2021 in Debre Elias District. Albendazole (400mg) was administered to assess efficacy and hookworm re-infection rate. Though the cure rate of single-dose albendazole was 81.7%, with an overall egg reduction rate of 92.5%, the re-infection rate of hookworm 18–24 weeks post-treatment was substantial at 21.4%. More effective intervention measures are thus needed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Tropical Doctor SAGE

Hookworm re-infection rate and efficacy of single-dose albendazole among pregnant women in Debre Elias District, Northwest Ethiopia: A single-arm trial

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References (17)

Publisher
SAGE
Copyright
© The Author(s) 2022
ISSN
0049-4755
eISSN
1758-1133
DOI
10.1177/00494755221080593
Publisher site
See Article on Publisher Site

Abstract

Hookworm is one of the soil-transmitted nematodes causing anaemia and low birth weight in pregnant women. This study aimed to assess albendazole efficacy and re-infection rate among pregnant women. A community-based cross-sectional study was conducted from February to September 2021 in Debre Elias District. Albendazole (400mg) was administered to assess efficacy and hookworm re-infection rate. Though the cure rate of single-dose albendazole was 81.7%, with an overall egg reduction rate of 92.5%, the re-infection rate of hookworm 18–24 weeks post-treatment was substantial at 21.4%. More effective intervention measures are thus needed.

Journal

Tropical DoctorSAGE

Published: Apr 1, 2022

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