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Daniel Krewski, Daniel Acosta, Melvin Andersen, Henry Anderson, John Bailar, Kim Boekelheide, Robert Brent, G. Charnley, Vivian Cheung, Sidney Green, Karl Kelsey, N. Kerkvliet, Abby Li, Lawrence McCray, Otto Meyer, Reid Patterson, William Pennie, R. Scala, Gina Solomon, Martin Stephens, James Yager, L. Zeise, Samuel McLaughlin (2010)
Toxicity Testing in the 21st Century: A Vision and a StrategyJournal of Toxicology and Environmental Health, Part B, 13
Nan Li, Yanfeng Liu, J. Qiu, Lingyan Zhong, N. Alépée, J. Cotovio, Zhenzi Cai (2017)
In vitro skin irritation assessment becomes a reality in China using a reconstructed human epidermis test method.Toxicology in vitro : an international journal published in association with BIBRA, 41
More and more countries are lining up to follow the EU's approach and implement a full ban on the sale of cosmetics that have been tested on animals, which has been the case in the EU since 2013. Besides animal welfare considerations, the need for mutual acceptance of data (MAD) and harmonisation of the global market have made the move toward non-animal testing a desirable general trend for countries worldwide. Over the last 10 years, the concept of alternative methods has been gradually developing in China. This has seen the harmonisation of relevant legislation, the organisation of various theoretical and hands-on training sessions, the exploration of method validation, the adoption of internationally recognised methods, the propagation of alternative testing standards, and an in-depth investigation into the potential use of in vitro methods in the biosciences. There are barriers to this progress, including the demand for a completely new infrastructure, the need to build technology capability, the requirement for a national standardisation system formed through international co-operation, and the lack of technical assistance to facilitate self-innovation. China is now increasing speed in harmonising its approach to the use of non-animal alternatives, accelerating technological development and attempting to incorporate non-animal, in vitro, testing methods into the national regulatory system.
Alternatives to Laboratory Animals – SAGE
Published: Dec 1, 2017
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