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ECVAM News & Views

ECVAM News & Views ATLA 36, 127, 2008 127 the increasing demand for carcinogenicity testing in ECVAM Workshop on Three Rs Japan. Facing a similar situation in Europe with the Approaches in the Production of REACH system, ECVAM’s input into the validation Biologicals activities of this project is crucial, in order to assure compatibility with ECVAM’s validation approaches, so The use of Three Rs methods in the quality control of that the Bhas CTA is a test fit for the REACH system biologicals is one of ECVAM’s key areas of interest. and other demands for testing. The production and quality control of fish vaccines is an issue of great animal welfare concern, since the procedures might inflict pain and distress on the ani- mals and large numbers of animals are used. The Visit by the Canadian Council on workshop aimed to identify the current requirements and possibilities for improvement, taking into Animal Care account the Three Rs. Fourteen external experts from industry, academia and competent authori- Alison Guy (CCAC, Ottawa, Canada) visited ECVAM ties/regulatory bodies attended the workshop. The to learn about the activities related to the reduction, outcome of the discussions will be published in a refinement and replacement of animal tests in workshop report. Europe. Key Publications Final Meeting of the ACuteTox FP6 Integrated Project Adler, S., Pellizzer, C., Hareng, L., Hartung, T. & Bremer, S. (2008). First steps in establishing a devel- ECVAM participated in the final meeting of the FP6 opmental toxicity test method based on human embry- IP ACuteTox, which was held from 19–22 February onic stem cells. Toxicology in Vitro 22, 200–211. 2008 in Konstanz, Germany. The last phase of the Bouvier d’Yvoire, M., Prieto, P., Blaauboer, B.J., Bois, project envisages the independent evaluation of the F.Y., Boobis, A., Brochot, C., Coecke, S., Freidig, A., datasets, in order to select the most appropriate Gundert-Remy, U., Hartung, T., Jacobs, M.N., Lavé, T., methods for inclusion in the testing strategy for Leahy, D.E., Lennernäs, H., Loizou, G.D., Meek, B., acute toxicity. Pease, C., Rowland, M., Spendiff, M., Yang, J. & Zeil - maker, M. (2007). Physiologically-based Kinetic Modelling (PBK Modelling): Meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop Advisory Committee Meeting for the 63. ATLA 35, 661–671. Bhas CTA Validation Study Hendriksen, C., Arciniega, J.L., Bruckner, L., Chev - alier, M., Coppens, E., Descamps, J., Duchêne, M., ECVAM took part in the meeting of the advisory com- Dusek, D.M., Halder, M., Kreeftenberg, H., Maes, A., mittee for the Bhas CTA validation study. The NEDO Redhead, K., Ravetkar, S.D., Spieser, J.M. & Swam, H. (New Energy and Industrial Technology Development Organization) project is a resourceful effort to further (2008). The consistency approach for the quality con- advance the cell transformation assay, in order to meet trol of vaccines. Biologicals 36, 73–77. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Alternatives to Laboratory Animals SAGE

ECVAM News & Views

Alternatives to Laboratory Animals , Volume 36 (2): 1 – May 1, 2008
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References (3)

Publisher
SAGE
Copyright
© 2008 Fund for the Replacement of Animals in Medical Experiments
ISSN
0261-1929
eISSN
2632-3559
DOI
10.1177/026119290803600203
Publisher site
See Article on Publisher Site

Abstract

ATLA 36, 127, 2008 127 the increasing demand for carcinogenicity testing in ECVAM Workshop on Three Rs Japan. Facing a similar situation in Europe with the Approaches in the Production of REACH system, ECVAM’s input into the validation Biologicals activities of this project is crucial, in order to assure compatibility with ECVAM’s validation approaches, so The use of Three Rs methods in the quality control of that the Bhas CTA is a test fit for the REACH system biologicals is one of ECVAM’s key areas of interest. and other demands for testing. The production and quality control of fish vaccines is an issue of great animal welfare concern, since the procedures might inflict pain and distress on the ani- mals and large numbers of animals are used. The Visit by the Canadian Council on workshop aimed to identify the current requirements and possibilities for improvement, taking into Animal Care account the Three Rs. Fourteen external experts from industry, academia and competent authori- Alison Guy (CCAC, Ottawa, Canada) visited ECVAM ties/regulatory bodies attended the workshop. The to learn about the activities related to the reduction, outcome of the discussions will be published in a refinement and replacement of animal tests in workshop report. Europe. Key Publications Final Meeting of the ACuteTox FP6 Integrated Project Adler, S., Pellizzer, C., Hareng, L., Hartung, T. & Bremer, S. (2008). First steps in establishing a devel- ECVAM participated in the final meeting of the FP6 opmental toxicity test method based on human embry- IP ACuteTox, which was held from 19–22 February onic stem cells. Toxicology in Vitro 22, 200–211. 2008 in Konstanz, Germany. The last phase of the Bouvier d’Yvoire, M., Prieto, P., Blaauboer, B.J., Bois, project envisages the independent evaluation of the F.Y., Boobis, A., Brochot, C., Coecke, S., Freidig, A., datasets, in order to select the most appropriate Gundert-Remy, U., Hartung, T., Jacobs, M.N., Lavé, T., methods for inclusion in the testing strategy for Leahy, D.E., Lennernäs, H., Loizou, G.D., Meek, B., acute toxicity. Pease, C., Rowland, M., Spendiff, M., Yang, J. & Zeil - maker, M. (2007). Physiologically-based Kinetic Modelling (PBK Modelling): Meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop Advisory Committee Meeting for the 63. ATLA 35, 661–671. Bhas CTA Validation Study Hendriksen, C., Arciniega, J.L., Bruckner, L., Chev - alier, M., Coppens, E., Descamps, J., Duchêne, M., ECVAM took part in the meeting of the advisory com- Dusek, D.M., Halder, M., Kreeftenberg, H., Maes, A., mittee for the Bhas CTA validation study. The NEDO Redhead, K., Ravetkar, S.D., Spieser, J.M. & Swam, H. (New Energy and Industrial Technology Development Organization) project is a resourceful effort to further (2008). The consistency approach for the quality con- advance the cell transformation assay, in order to meet trol of vaccines. Biologicals 36, 73–77.

Journal

Alternatives to Laboratory Animals – SAGE

Published: May 1, 2008

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