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S. Kaesler, Y. Skabytska, Ko-Ming Chen, W. Kempf, T. Volz, M. Köberle, F. Wölbing, U. Hein, T. Hartung, C. Kirschning, M. Röcken, T. Biedermann (2016)
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ATLA 44, 309–310, 2016 309 learned in this study that that is not always the CAAT Researchers Track Metabolic case.” The discovery came about when scientists Pathways to Find Drug Combinations at Johns Hopkins Bloomberg School of Public for Pancreatic Cancer Health and Brown University were performing experiments for the Human Toxome Project. For Cancer researchers have long observed the value this experiment, the researchers worked with of treating patients with combinations of anti- cells from the MCF-7 line, a well-established cancer drugs that work better than single drug breast cancer line isolated in 1970. It has been treatments. Johns Hopkins scientists have rec - used in original research published in more than ently reported, in the Proceedings of the National 23,000 scientific articles. To perform identical Academy of Sciences of the USA, the results of a experiments, researchers from the two laborato- study based on a method that they used to track ries purchased frozen vials of cells of the same lot metabolic pathways heavily favoured by cancer from the same cell bank. As a standard precau- cells. The results provide scientific evidence for tion to make sure that the cells were not contam- combining anti-cancer drugs, including
Alternatives to Laboratory Animals – SAGE
Published: Sep 1, 2016
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