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CAAT News & Views

CAAT News & Views ATLA 44, 309–310, 2016 309 learned in this study that that is not always the CAAT Researchers Track Metabolic case.” The discovery came about when scientists Pathways to Find Drug Combinations at Johns Hopkins Bloomberg School of Public for Pancreatic Cancer Health and Brown University were performing experiments for the Human Toxome Project. For Cancer researchers have long observed the value this experiment, the researchers worked with of treating patients with combinations of anti- cells from the MCF-7 line, a well-established cancer drugs that work better than single drug breast cancer line isolated in 1970. It has been treatments. Johns Hopkins scientists have rec - used in original research published in more than ently reported, in the Proceedings of the National 23,000 scientific articles. To perform identical Academy of Sciences of the USA, the results of a experiments, researchers from the two laborato- study based on a method that they used to track ries purchased frozen vials of cells of the same lot metabolic pathways heavily favoured by cancer from the same cell bank. As a standard precau- cells. The results provide scientific evidence for tion to make sure that the cells were not contam- combining anti-cancer drugs, including http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Alternatives to Laboratory Animals SAGE

CAAT News & Views

Alternatives to Laboratory Animals , Volume 44 (4): 2 – Sep 1, 2016

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References (15)

Publisher
SAGE
Copyright
© 2016 Fund for the Replacement of Animals in Medical Experiments
ISSN
0261-1929
eISSN
2632-3559
DOI
10.1177/026119291604400402
Publisher site
See Article on Publisher Site

Abstract

ATLA 44, 309–310, 2016 309 learned in this study that that is not always the CAAT Researchers Track Metabolic case.” The discovery came about when scientists Pathways to Find Drug Combinations at Johns Hopkins Bloomberg School of Public for Pancreatic Cancer Health and Brown University were performing experiments for the Human Toxome Project. For Cancer researchers have long observed the value this experiment, the researchers worked with of treating patients with combinations of anti- cells from the MCF-7 line, a well-established cancer drugs that work better than single drug breast cancer line isolated in 1970. It has been treatments. Johns Hopkins scientists have rec - used in original research published in more than ently reported, in the Proceedings of the National 23,000 scientific articles. To perform identical Academy of Sciences of the USA, the results of a experiments, researchers from the two laborato- study based on a method that they used to track ries purchased frozen vials of cells of the same lot metabolic pathways heavily favoured by cancer from the same cell bank. As a standard precau- cells. The results provide scientific evidence for tion to make sure that the cells were not contam- combining anti-cancer drugs, including

Journal

Alternatives to Laboratory AnimalsSAGE

Published: Sep 1, 2016

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