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BOOK REVIEWS fluids and solids kinetics in haemodialysis, the cyclophosphamide at the tumour site. This mechanical evaluation of spondylolysis, and the approach causes less bone marrow suppression simulation of back pain. than is generally the case with cyclophosphamide The use of other model simulations, such as alone. those for three-dimensional models of tumour I found this book deficient in one sense - it growth and the simulation of the dynamics of neu lacks an overview of GST nomenclature and, ron degeneration in motor neurone disease, would throughout the volume, various GST naming sys seem to have more direct relevance for acting as tems are used. Hence, it could be difficult to follow replacements for laboratory animal experiments. for a reader who is unfamiliar with the various There are also chapters on modelling bone regen nomenclatures. eration and modelling the effects of bone implants From the standpoint of a worker in in vitro tox and prostheses, which will be relevant for those icology, the GSTs represent a much neglected area working on biocompatability. of research, especially when compared to meta This text is for the specialist reader interested in bolic activation. Perhaps more consideration the potential of computerised and mathematical
Alternatives to Laboratory Animals – SAGE
Published: Jul 1, 1997
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