Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Book Review: The use of Immuno-Adjuvants in Animals in Australia and New Zealand

Book Review: The use of Immuno-Adjuvants in Animals in Australia and New Zealand 708 ATLA 27, 708, 1999 Book Review THE USE OF IMMUNO-ADJUVANTS adjuvant is again acknowledged, but the use of alternatives, whenever available, is suggested. IN ANIMALS IN AUSTRALIA AND It is recommended that researchers intending to NEW ZEALAND use adjuvants in animals should consult the Australian and New Zealand Council for the Care available scientific literature on the compara- of Animals in Research and Teaching tive efficacy and reactogenicity of various adju- (ANZCCART), Glen Osmond, SA, Australia, 1998 vants, before the use of Freund’s adjuvant is 35pp. proposed. The publication contains a compre- ISBN 0-646-24923-1 hensive list of references, which can be used for this purpose. This publication was produced as a result of a While extensive information is provided on the workshop on the use of Freund’s adjuvant, which use of Freund’s adjuvant, no guidelines (for exam- was held in Melbourne in 1994. It has been pro- ple, on maximum volume or administration route) duced to serve as a valuable set of guidelines for are provided for the use of other adjuvants in ani- adjuvant use in animals in Australia and New mals. Since the publication is based on informa- Zealand. The guidelines on injection route and tion from the participants and articles from maximum volume given reflect the information various authors, recommendations are not consis- provided by the 40 participants at the workshop, tent throughout the text, especially with respect to and do not necessarily reflect the view of ANZ- the preferred administration route. CCART or its member organisations. One of the major messages from the workshop is The current use of Freund’s adjuvant and its that most of the adverse effects of Freund’s adju- alternatives are reviewed in two of the articles. It vant can be avoided by using small volumes. It is is concluded in both articles that the use of noted, however, that alternatives are available, Freund’s adjuvant is long-established and effec- and should be considered, as they might be ade- tive. An interesting literature review on the quate in some applications. adverse effects of immuno-adjuvants is also included. In this review, the value of Freund’s Marlies Leenaars http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Alternatives to Laboratory Animals SAGE

Book Review: The use of Immuno-Adjuvants in Animals in Australia and New Zealand

Leenaars, Marlies
Alternatives to Laboratory Animals , Volume 27 (4): 1 – Jul 1, 1999
Download PDF
1 page

Loading next page...
 
/lp/sage/book-review-the-use-of-immuno-adjuvants-in-animals-in-australia-and-Xq26x5a6mA

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
SAGE
Copyright
© 1999 Fund for the Replacement of Animals in Medical Experiments
ISSN
0261-1929
eISSN
2632-3559
DOI
10.1177/026119299902700401
Publisher site
See Article on Publisher Site

Abstract

708 ATLA 27, 708, 1999 Book Review THE USE OF IMMUNO-ADJUVANTS adjuvant is again acknowledged, but the use of alternatives, whenever available, is suggested. IN ANIMALS IN AUSTRALIA AND It is recommended that researchers intending to NEW ZEALAND use adjuvants in animals should consult the Australian and New Zealand Council for the Care available scientific literature on the compara- of Animals in Research and Teaching tive efficacy and reactogenicity of various adju- (ANZCCART), Glen Osmond, SA, Australia, 1998 vants, before the use of Freund’s adjuvant is 35pp. proposed. The publication contains a compre- ISBN 0-646-24923-1 hensive list of references, which can be used for this purpose. This publication was produced as a result of a While extensive information is provided on the workshop on the use of Freund’s adjuvant, which use of Freund’s adjuvant, no guidelines (for exam- was held in Melbourne in 1994. It has been pro- ple, on maximum volume or administration route) duced to serve as a valuable set of guidelines for are provided for the use of other adjuvants in ani- adjuvant use in animals in Australia and New mals. Since the publication is based on informa- Zealand. The guidelines on injection route and tion from the participants and articles from maximum volume given reflect the information various authors, recommendations are not consis- provided by the 40 participants at the workshop, tent throughout the text, especially with respect to and do not necessarily reflect the view of ANZ- the preferred administration route. CCART or its member organisations. One of the major messages from the workshop is The current use of Freund’s adjuvant and its that most of the adverse effects of Freund’s adju- alternatives are reviewed in two of the articles. It vant can be avoided by using small volumes. It is is concluded in both articles that the use of noted, however, that alternatives are available, Freund’s adjuvant is long-established and effec- and should be considered, as they might be ade- tive. An interesting literature review on the quate in some applications. adverse effects of immuno-adjuvants is also included. In this review, the value of Freund’s Marlies Leenaars

Journal

Alternatives to Laboratory Animals – SAGE

Published: Jul 1, 1999

There are no references for this article.