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- Publisher
- SAGE
- Copyright
- © 1989 Fund for the Replacement of Animals in Medical Experiments
- ISSN
- 0261-1929
- eISSN
- 2632-3559
- DOI
- 10.1177/026119298901600323
- Publisher site
- See Article on Publisher Site
Abstract
BOOK REVIEWS but in introducing new concepts into the laboratory. Section I contains five papers on promotion, The requirement that the Secretary of State forms involving the classical mouse skin and rat liver a scientific judgement on the merit of the work to systems, plus work on the rat bladder and an be undertaken is one example, and others are the interesting paper on acute cell injury, with linking of pain (including suffering, distress or emphasis on the deregulation of calcium lasting harm) to the purpose and importance of the metabolism. work undertaken by imposing severity limits of The second section contains six papers on forced mild, moderate or substantial on project licences, cell proliferation, which deal with the role of orotic and the appointment of three named persons - acid as a promoter in liver carcinogenesis, the the Certificate holder, the person with importance of liver growth in responsibility for the day-to-day care of animals, hepatocarcinogenesis, chemically-induced cell and the veterinary surgeon with responsibility for proliferation in the kidney, the part played by the welfare and well-being of animals. In each case, cytotoxicity, and the value of measuring cell replication. there is a statutory responsibility which applies to
Journal
Alternatives to Laboratory Animals – SAGE
Published: Mar 1, 1989