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Journal of MANAGED CARE MANAGED CARE IN UROLOGY Alternative prostate treatments: drugs Gordon Williams Consultant Urologist, Hammersmith Hospital INTRODUCTION These figures are important when one considers the results of treatment of prostatic obstruction. Treatment The only way to prevent benign prostatic hyperplasia must not only be cost-effective and relieve the (BPH) , a disease that affects almost all men over the symptoms and the bother they cause, but also provide age of 40 years, is castration at, or before, puberty. objective evidence ofimprovements in peak urine flow, Though BPH is an almost invariable consequence of reduction of residual urine and diminished detrusor ageing only a small proportion of men develop pressure. symptoms requiring treatment. The prostate may cause obstruction to urine flow in The hyperplastic process affects both the epithelium 2 ways. The first, due to a static effect by the bulk of and stroma of the prostate and will usually result in an the prostate, is related to the amount of stroma and increase in prostatic size. However, an increase in size epithelium - larger prostates tending to contain more is not necessary to produce the obstructive and irritative epithelium. In the second, obstruction is caused by a
Journal of Managed Care – SAGE
Published: Apr 1, 1997
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