Introduction: Future Research Directions in the Epidemiology of Human Papillomavirus and Cancer
Abstract
Introduction: Future Research Directions in the Epidemiology of Human Papillomavirus and Cancer var callbackToken='505ED1C3C5C089E'; var subCode='oupjournal_sub'; var gAuthTimeStamp = '2015-11-11T15:19:59.932-08:00'; var gSessionId = 'odAUgajU6g-5tttmq1xChA'; var gAuthzRequired = 'false'; var gAuthnMethods1 = 'ip'; var gAuthnMethods2 = 'ip'; var gAuthnIPs = '64.13.143.102'; var gAuthnIndividuals = ''; var gAuthnInstitutions = '151647456'; MathJax.Hub.Config({ tex2jax: { inlineMath: (("$","$"),("\\(","\\)")), processClass: "tex2jax_process|mathjax" } }); MathJax.Hub.Queue(function() { gColTempResize = true; fixColHeights(1); gColTempResize = false; }); var siqDOI = encodeURIComponent(""); var siqIsOpenAccess = encodeURIComponent(""); var siqPubDate = encodeURIComponent("20030601"); if (siqDOI.length == 0) { siqDOI = "UNKNOWN"; } if (gAuthnIndividuals.length != 0) { if (gAuthnInstitutions.length != 0) { authnEntity = encodeURIComponent(gAuthnIndividuals + ',' + gAuthnInstitutions); } else { authnEntity = encodeURIComponent(gAuthnIndividuals); } } else { authnEntity = encodeURIComponent(gAuthnInstitutions); } var commonString = 'authSessionId=' + gSessionId + String.fromCharCode(0x26) + 'authzRequired=' + gAuthzRequired + String.fromCharCode(0x26) + 'authentication_method=' + encodeURIComponent(gAuthnMethods2) + String.fromCharCode(0x26) + 'authnIPs=' + gAuthnIPs + String.fromCharCode(0x26) + 'authnInstitutions=' + authnEntity; var gPageId = "pageid-content"; var gVariant = "extract"; // Not completely done var eventType = "extract"; var accessType; if (siqIsOpenAccess == 'true') { accessType = 'SOA'; } else { accessType = 'subscription'; } var NTPT_PGEXTRA = commonString + String.fromCharCode(0x26) + 'event_type=' + eventType + String.fromCharCode(0x26) + 'publication_date=' + siqPubDate + String.fromCharCode(0x26) + 'access_type=' + accessType + String.fromCharCode(0x26) + 'doi=' + siqDOI ; // alert("NTPT_PGEXTRA is " + NTPT_PGEXTRA); We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Find out more Skip Navigation Oxford Journals Contact Us My Basket My Account JNCI Monographs About This Journal Contact This Journal Subscriptions View Current Issue (Volume 2015 Issue 51 May 2015) Archive Search Institution: :: Sign In as Personal Subscriber Oxford Journals Medicine & Health JNCI Monographs Volume 2003 Issue 31 Pp. 1-2. Introduction: Future Research Directions in the Epidemiology of Human Papillomavirus and Cancer F. Xavier Bosch , Mark Schiffman and Diane Solomon Affiliations of authors: F. X. Bosch, Epidemiology and Cancer Registration Unit, Catalan Institute of Oncology, Avda. Gran Via, s/n Km 2,7,08907 L’Hospitalet de Llobregat, Barcelona, Spain; M. Schiffman, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD; D. Solomon, Breast and Gynecologic Cancer Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD. Correspondence to: F. Xavier Bosch, M.D., Epidemiology and Cancer Registration Unit, Catalan Institute of Oncology, Avda. Gran Via, s/n Km 2,7,08907 L’Hospitalet de Llobregat, Barcelona, Spain (e-mail: x.bosch@ico.scs.es ). The causal link between human papillomavirus (HPV) and cervical cancer is now established beyond doubt and the association has become an important model of viral carcinogenesis. The corollary in practical terms is that cervical cancer does not occur without the persistent presence of HPV-DNA. Research on HPV-negative cervical cancers is no longer a priority, because such cases are exceedingly rare (i.e., the non-epithelial cervical cancer types) and usually the result of measurement error of some kind. The implications for cancer prevention are revolutionary. Screening with HPV tests that cover approximately 15 oncogenic or ”high-risk” HPV types can effectively target all women with prevalent or incipient cervical cancer worldwide. Likewise, polyvalent prophylactic HPV vaccines should be able to prevent a predictable fraction of the cases of cervical cancer in a given population. In reaction to new etiologic evidence and improved technology, cervical cancer epidemiologic and preventive efforts are being reshaped throughout the world, based on the resource levels of the different regions. This monograph was designed to consider what studies on HPV and cancer are most likely to be useful in the decade ahead. With regard to etiology, future molecular epidemiologic research will concentrate on the cofactors for HPV carcinogenesis as well as on the steps and mechanisms by which an extremely … (Full Text of this Article) « Previous | Next Article » Table of Contents This Article J Natl Cancer Inst Monogr (2003) 2003 (31): 1-2. This article appears in: Future Directions in Epidemiologic and Preventive Research on Human Papillomaviruses and Cancer » Extract Free Full Text (HTML) Free Full Text (PDF) Free Classifications Article Services Article metrics Alert me when cited Alert me if corrected Find similar articles Similar articles in Web of Science Similar articles in PubMed Add to my archive Download citation Request Permissions Citing Articles Load citing article information Citing articles via CrossRef Citing articles via Scopus Citing articles via Web of Science Citing articles via Google Scholar Google Scholar Articles by Bosch, F. X. Articles by Solomon, D. Search for related content PubMed PubMed citation Articles by Bosch, F. X. Articles by Schiffman, M. Articles by Solomon, D. Related Content Load related web page information Share Email this article CiteULike Delicious Facebook Google+ Mendeley Twitter What's this? 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