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Inference-based correction of multi-site height and weight measurement data in the All of Us research program

Inference-based correction of multi-site height and weight measurement data in the All of Us... ObjectiveMeasurement and data entry of height and weight values are error prone. Aggregation of medical record data from multiple sites creates new challenges prompting the need to identify and correct errant values. We sought to characterize and correct issues with height and weight measurement values within the All of Us (AoU) Research Program.Materials and MethodsUsing the AoU Researcher Workbench, we assessed site-level measurement value distributions to infer unit types. We also used plausibility checks with exceptions for conditions with possible outlier values, eg obesity, and assessed for excess deviation within individual participant’s records.Results15.8% of height and 22.4% of weight values had missing unit type information.DiscussionWe identified several measurement unit related issues: the use of different units of measure within and between sites, missing units, and incorrect labeling of units. Failure to account for these in patient data repositories may lead to erroneous study results and conclusions.ConclusionDiscrepancies in height and weight measurement data may arise from missing or mislabeled units. Using site- and participant-level analyses while accounting for outlier value-associated clinical conditions, we can infer measurement units and apply corrections. These methods are adaptable and expandable within AoU and other data repositories. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of the American Medical Informatics Association Oxford University Press

Inference-based correction of multi-site height and weight measurement data in the All of Us research program

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References (6)

Publisher
Oxford University Press
Copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For permissions, please email: journals.permissions@oup.com
ISSN
1067-5027
eISSN
1527-974X
DOI
10.1093/jamia/ocab251
Publisher site
See Article on Publisher Site

Abstract

ObjectiveMeasurement and data entry of height and weight values are error prone. Aggregation of medical record data from multiple sites creates new challenges prompting the need to identify and correct errant values. We sought to characterize and correct issues with height and weight measurement values within the All of Us (AoU) Research Program.Materials and MethodsUsing the AoU Researcher Workbench, we assessed site-level measurement value distributions to infer unit types. We also used plausibility checks with exceptions for conditions with possible outlier values, eg obesity, and assessed for excess deviation within individual participant’s records.Results15.8% of height and 22.4% of weight values had missing unit type information.DiscussionWe identified several measurement unit related issues: the use of different units of measure within and between sites, missing units, and incorrect labeling of units. Failure to account for these in patient data repositories may lead to erroneous study results and conclusions.ConclusionDiscrepancies in height and weight measurement data may arise from missing or mislabeled units. Using site- and participant-level analyses while accounting for outlier value-associated clinical conditions, we can infer measurement units and apply corrections. These methods are adaptable and expandable within AoU and other data repositories.

Journal

Journal of the American Medical Informatics AssociationOxford University Press

Published: Dec 3, 2021

Keywords: electronic health records/statistics and numerical data; body mass index; body height; body weight; biomedical research

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