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Expanding interactome analyses beyond model eukaryotes

Expanding interactome analyses beyond model eukaryotes Interactome analyses have traditionally been applied to yeast, human and other model organisms due to the availability of protein–protein interaction data for these species. Recently, these techniques have been applied to more diverse species using computational interaction prediction from genome sequence and other data types. This review describes the various types of computational interactome networks that can be created and how they have been used in diverse eukaryotic species, highlighting some of the key interactome studies in non-model organisms. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Briefings in Functional Genomics Oxford University Press

Expanding interactome analyses beyond model eukaryotes

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References (476)

Publisher
Oxford University Press
Copyright
© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com
ISSN
2041-2649
eISSN
2041-2657
DOI
10.1093/bfgp/elac007
Publisher site
See Article on Publisher Site

Abstract

Interactome analyses have traditionally been applied to yeast, human and other model organisms due to the availability of protein–protein interaction data for these species. Recently, these techniques have been applied to more diverse species using computational interaction prediction from genome sequence and other data types. This review describes the various types of computational interactome networks that can be created and how they have been used in diverse eukaryotic species, highlighting some of the key interactome studies in non-model organisms.

Journal

Briefings in Functional GenomicsOxford University Press

Published: May 12, 2022

Keywords: systems biology; integrative bioinformatics; interactomics; eukaryotes; non-models; network biology

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