Abstract

APPLIED IN VITRO TOXICOLOGY Volume 1, Number 4, 2015 ª Mary Ann Liebert, Inc. DOI: 10.1089/aivt.2015.29000.abstracts Abstracts In Vitro Toxicology Society Annual Meeting November 10–11, 2015 Birmingham, United Kingdom These abstracts were presented at the 2015 annual meeting of the UK In Vitro Toxicology Society (IVTS). The meeting was hosted at Birmingham, UK on November 10–11, 2015. The main session topics included hepatoxicology, inhalation toxicology, devel- opmental and reproductive toxicology, and neurotoxicology. The IVTS (www.ivts.org.uk) was founded in 1988 to support scientists active in the study, practice or development of in vitro toxicology. Speaker Abstracts S-1. The lecture will give a state of the art view of the current stage and results in the development of these new systems. Evaluation of human liver microtissues in hepatotoxicity screening Dominic Williams S-3. Mechanistic biomarkers and their application AstraZeneca, UK to the study of drug induced liver injury in vitro Drug-induced liver injury (DILI) is a major cause of attrition Daniel J. Antoine during drug development and drug withdrawal. Hence the need MRC Centre for Drug Safety Science, Department of Molecular for predictive toxicology screening assays which enable early and Clinical Pharmacology, University of Liverpool, UK identification and deselection of compounds that