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Pharmacology of antioxidants: how do they work and what are the benefits?

Pharmacology of antioxidants: how do they work and what are the benefits? AbstractAntioxidants are increasing in popularity and are now commonly used in skin care products. It is often thought that antioxidants are miracle substances that will protect us from ageing and disease, yet few realise what they are how they work and what exactly they are protecting our body against. This article will discuss what antioxidants are, the action of free radicals within the body and cells and what effects they have when oxidative stress occurs and the damage they cause accumulates. The free radical theory of ageing suggests that cells accumulate this free radical damage over time and that long-term damage leads to the release of inflammatory molecules and visual signs of ageing such as loss of elasticity and skin tone. Damage caused by free radicals can also contribute to major illnesses such as Parkinson's disease. It has been shown that a diet rich in fruits and vegetables, which have high antioxidant levels can increase lifespan and give protection against certain diseases. It could therefore be assumed that antioxidants, with their free radical neutralising properties, could also be used as a preventative measure. Supportive studies for the use of antioxidants discussed in this article however have not been able to confirm that it is the antioxidant content that exerts this affect. It could be assumed that you could take an antioxidant with a high ORAC value and formulate a topical product, however many factors need to be taken into consideration, including pH, stability, base, oxygen exposure and ingredient percentages. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Aesthetic Nursing Mark Allen Group

Pharmacology of antioxidants: how do they work and what are the benefits?

Journal of Aesthetic Nursing , Volume 1 (6): 7 – Dec 1, 2012

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Publisher
Mark Allen Group
Copyright
Copyright © 2012 MA Healthcare Limited
ISSN
2050-3717
eISSN
2052-2878
DOI
10.12968/joan.2012.1.6.299
Publisher site
See Article on Publisher Site

Abstract

AbstractAntioxidants are increasing in popularity and are now commonly used in skin care products. It is often thought that antioxidants are miracle substances that will protect us from ageing and disease, yet few realise what they are how they work and what exactly they are protecting our body against. This article will discuss what antioxidants are, the action of free radicals within the body and cells and what effects they have when oxidative stress occurs and the damage they cause accumulates. The free radical theory of ageing suggests that cells accumulate this free radical damage over time and that long-term damage leads to the release of inflammatory molecules and visual signs of ageing such as loss of elasticity and skin tone. Damage caused by free radicals can also contribute to major illnesses such as Parkinson's disease. It has been shown that a diet rich in fruits and vegetables, which have high antioxidant levels can increase lifespan and give protection against certain diseases. It could therefore be assumed that antioxidants, with their free radical neutralising properties, could also be used as a preventative measure. Supportive studies for the use of antioxidants discussed in this article however have not been able to confirm that it is the antioxidant content that exerts this affect. It could be assumed that you could take an antioxidant with a high ORAC value and formulate a topical product, however many factors need to be taken into consideration, including pH, stability, base, oxygen exposure and ingredient percentages.

Journal

Journal of Aesthetic NursingMark Allen Group

Published: Dec 1, 2012

There are no references for this article.