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The Induction of the Shwartzman Phenomenon in the Rabbit Cornea

The Induction of the Shwartzman Phenomenon in the Rabbit Cornea R a u s ,R .: O phthalm ologica 132, 137, 1956 (Eye Hospital Rotterdam ¡Dir.: Dr. H. J. Flieringa].) T h e I n d u c tio n o f t h e S h w a r tz m a n P h e n o m e n o n in t h e R a b b i t C o rn e a By R. RAUS. The Shwartzman phenomenon has been previously brought about in the vascularized cornea of the rabbit. G. Fabiani and A. Gauthier (1), achieved it in a vascularized leucoma. We used the technique described by Langham (2) to vascularize the cornea. Injections of a sufficient quantity of alloxan through the sclera into the anterior chamber cause considerable corneal oedema. After 3 to 4 days, the oedematous cornea is invaded by a profuse vascularization, originating from the hyperaemic vessels of the limbus (Fig. 1). At the beginning of the third week after the intro­ duction of the alloxan, the vascularization, which is centripetal, is half-way, but the noil-vascularized area has not reached the centre of the cornea. This technique was used by us to obtain the Shwartzman phenomenon. A broth http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Ophthalmologica Karger

The Induction of the Shwartzman Phenomenon in the Rabbit Cornea

Ophthalmologica , Volume 132 (3): 4 – Jan 1, 2010

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Publisher
Karger
Copyright
© 1956 S. Karger AG, Basel
ISSN
0030-3755
eISSN
1423-0267
DOI
10.1159/000302941
Publisher site
See Article on Publisher Site

Abstract

R a u s ,R .: O phthalm ologica 132, 137, 1956 (Eye Hospital Rotterdam ¡Dir.: Dr. H. J. Flieringa].) T h e I n d u c tio n o f t h e S h w a r tz m a n P h e n o m e n o n in t h e R a b b i t C o rn e a By R. RAUS. The Shwartzman phenomenon has been previously brought about in the vascularized cornea of the rabbit. G. Fabiani and A. Gauthier (1), achieved it in a vascularized leucoma. We used the technique described by Langham (2) to vascularize the cornea. Injections of a sufficient quantity of alloxan through the sclera into the anterior chamber cause considerable corneal oedema. After 3 to 4 days, the oedematous cornea is invaded by a profuse vascularization, originating from the hyperaemic vessels of the limbus (Fig. 1). At the beginning of the third week after the intro­ duction of the alloxan, the vascularization, which is centripetal, is half-way, but the noil-vascularized area has not reached the centre of the cornea. This technique was used by us to obtain the Shwartzman phenomenon. A broth

Journal

OphthalmologicaKarger

Published: Jan 1, 2010

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