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Renal Cell Carcinoma: An Extraordinary Case of Cutaneous Metastasis 21 Years after Radical Nephrectomy

Renal Cell Carcinoma: An Extraordinary Case of Cutaneous Metastasis 21 Years after Radical... There are reports of renal cell carcinoma (RCC) metastases in almost every part of the body. Skin metastases due to RCC are a rare condition. Only 3.4% of all RCCs give rise to metastases in the skin. We present a 73-year-old man who developed a solitary cutaneous metastasis 21 years after radical nephrectomy. A computed tomography scan also revealed two nodules in the lungs and a mid-pole mass in the right kidney. Complete local excision of the lesion was performed. The patient was started on oral treatment with sunitinib. At the 24-month review a control computed tomography revealed that the lung lesions had completely disappeared but the size of the renal mass had not changed. To our knowledge this is the only reported case of cutaneous metastasis appearing more than 20 years after radical treatment. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Urology Karger

Renal Cell Carcinoma: An Extraordinary Case of Cutaneous Metastasis 21 Years after Radical Nephrectomy

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References (13)

Publisher
Karger
Copyright
© 2011 S. Karger AG, Basel
ISSN
1661-7649
eISSN
1661-7657
DOI
10.1159/000327481
Publisher site
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Abstract

There are reports of renal cell carcinoma (RCC) metastases in almost every part of the body. Skin metastases due to RCC are a rare condition. Only 3.4% of all RCCs give rise to metastases in the skin. We present a 73-year-old man who developed a solitary cutaneous metastasis 21 years after radical nephrectomy. A computed tomography scan also revealed two nodules in the lungs and a mid-pole mass in the right kidney. Complete local excision of the lesion was performed. The patient was started on oral treatment with sunitinib. At the 24-month review a control computed tomography revealed that the lung lesions had completely disappeared but the size of the renal mass had not changed. To our knowledge this is the only reported case of cutaneous metastasis appearing more than 20 years after radical treatment.

Journal

Current Urology – Karger

Published: Jan 1, 2011

Keywords: Renal cell carcinoma; Cutaneous metastasis; Antiangiogenics; Sunitinib

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