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Predictive Factors for Benign Lesions in Partially or Radically Resected Kidneys in a Single Independent Cancer Center

Predictive Factors for Benign Lesions in Partially or Radically Resected Kidneys in a Single... Objective: To assess the incidence and predictive factors of benign renal lesions in surgical specimens obtained at our institution. Methods: We carried out a retrospective assessment of 96 renal nodules, diagnosed by dynamic multi-detector row helical computed tomography, and resected by either radical or partial nephrectomy between January 2004 and November 2011. The incidence of benign lesions in 1-cm increments of diameter was determined and the predictive factors for these lesions were then evaluated. Results: Of the 96 nodules, histology confirmed that 13 (13.5%) were benign. The incidence of benign lesions was 25.0% for nodules <1 cm, 23.8% for nodules 1-1.9 cm, 11.5% for nodules 2-2.9 cm, 7.7% for nodules 3-3.9 cm, and 7.1% for nodules ≥4 cm. Multivariate analysis showed that younger age (<60 years; odds ratio [OR] = 5.23), female gender (OR = 4.78), and smaller nodule size (<3 cm; OR = 6.14) were significant predictive factors for benign lesions. Conclusions: The incidence of benign lesions in this study (13.5% of total cases) was relatively low compared with recent studies from Western countries that reported an incidence of 15-20%. Significant predictive factors for benign lesions included younger age, female gender, and smaller tumor size. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Urology Karger

Predictive Factors for Benign Lesions in Partially or Radically Resected Kidneys in a Single Independent Cancer Center

Current Urology , Volume 7 (2): 5 – Jan 1, 2013

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References (16)

Publisher
Karger
Copyright
© 2013 S. Karger AG, Basel
ISSN
1661-7649
eISSN
1661-7657
DOI
10.1159/000356252
Publisher site
See Article on Publisher Site

Abstract

Objective: To assess the incidence and predictive factors of benign renal lesions in surgical specimens obtained at our institution. Methods: We carried out a retrospective assessment of 96 renal nodules, diagnosed by dynamic multi-detector row helical computed tomography, and resected by either radical or partial nephrectomy between January 2004 and November 2011. The incidence of benign lesions in 1-cm increments of diameter was determined and the predictive factors for these lesions were then evaluated. Results: Of the 96 nodules, histology confirmed that 13 (13.5%) were benign. The incidence of benign lesions was 25.0% for nodules <1 cm, 23.8% for nodules 1-1.9 cm, 11.5% for nodules 2-2.9 cm, 7.7% for nodules 3-3.9 cm, and 7.1% for nodules ≥4 cm. Multivariate analysis showed that younger age (<60 years; odds ratio [OR] = 5.23), female gender (OR = 4.78), and smaller nodule size (<3 cm; OR = 6.14) were significant predictive factors for benign lesions. Conclusions: The incidence of benign lesions in this study (13.5% of total cases) was relatively low compared with recent studies from Western countries that reported an incidence of 15-20%. Significant predictive factors for benign lesions included younger age, female gender, and smaller tumor size.

Journal

Current UrologyKarger

Published: Jan 1, 2013

Keywords: Benign nodule Predictive factor; Renal cancer

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