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Do Beta-Blockers Cause Vasospasm?

Do Beta-Blockers Cause Vasospasm? The action of Β-blockers on papillary blood flow is quite controversial. Because there is a known relationship between digital and ocular vasospasm, we measured digital blood flow by laser-Doppler methods as a peripheral index of ocular vasospastic disorders. Thus, the effects of cardioselective (betaxolol) and noncardioselective (timolol) Β-blockers on peripheral blood flow in healthy volunteers were evaluated. Neither Β-blocker lowered peripheral blood flow; for betaxolol, there was even a significant increase compared to no medication. No significant differences between betaxolol and timolol were seen. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Ophthalmologica Karger

Do Beta-Blockers Cause Vasospasm?

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Publisher
Karger
Copyright
© 1993 S. Karger AG, Basel
ISSN
0030-3755
eISSN
1423-0267
DOI
10.1159/000310362
Publisher site
See Article on Publisher Site

Abstract

The action of Β-blockers on papillary blood flow is quite controversial. Because there is a known relationship between digital and ocular vasospasm, we measured digital blood flow by laser-Doppler methods as a peripheral index of ocular vasospastic disorders. Thus, the effects of cardioselective (betaxolol) and noncardioselective (timolol) Β-blockers on peripheral blood flow in healthy volunteers were evaluated. Neither Β-blocker lowered peripheral blood flow; for betaxolol, there was even a significant increase compared to no medication. No significant differences between betaxolol and timolol were seen.

Journal

OphthalmologicaKarger

Published: Jan 1, 2010

Keywords: Beta-blockers; Timolol; Betaxolol; Laser-Doppler velocimetry

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