Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Cystatin C and Seminal Parameter Evaluation in Patients with End-Stage Renal Disease

Cystatin C and Seminal Parameter Evaluation in Patients with End-Stage Renal Disease Objective: We aimed to investigate the possible relationship between seminal parameters and cystatin C seminal levels in an infertility evaluation of chronic hemodialysis patients. Materials and Methods: This was a cross-sectional study, aged 18-60 years, in a group of 60 men undergoing hemodialysis (case) for more than 6 months, and a group of 15 healthy men (control) without clinical or laboratory signs of genitourinary tract infection. We performed a spermogram, hormonal profile, and assessment of leukocytes and cystatin levels in the semen. Results: The ages in the case and control were similar (p = 0.060).The seminal cystatin was significantly different between the case group and control group (41.16 ± 26.59 vs. 79.00 ± 05.68 mg/l, respectively, p < 0.001) and between normospermia and oligospermia (83.50 ± 02.40 vs. 30.34 ± 02.52 mg/l, respectively, p < 0.001). The mean seminal cystatin levels identified by the degrees of oligospermia (severe, moderate, and slim) were similar to each other (p > 0.05) and significantly different (p < 0.05) in relation to normospermia in the case group. The seminal cystatin levels positively correlated (p < 0.05) with sperm motility and sperm density. Conclusion: Seminal cystatin levels are associated with the numerical and motility changes evidenced in the spermogram and may be of help in the initial evaluation of clinical suspicion of sub-fertility and infertility. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Urology Karger

Cystatin C and Seminal Parameter Evaluation in Patients with End-Stage Renal Disease

Loading next page...
 
/lp/karger/cystatin-c-and-seminal-parameter-evaluation-in-patients-with-end-stage-obG2RmfXNx
Publisher
Karger
Copyright
© 2020 The Author(s) Published by S. Karger AG, Basel
ISSN
1661-7649
eISSN
1661-7657
DOI
10.1159/000499241
Publisher site
See Article on Publisher Site

Abstract

Objective: We aimed to investigate the possible relationship between seminal parameters and cystatin C seminal levels in an infertility evaluation of chronic hemodialysis patients. Materials and Methods: This was a cross-sectional study, aged 18-60 years, in a group of 60 men undergoing hemodialysis (case) for more than 6 months, and a group of 15 healthy men (control) without clinical or laboratory signs of genitourinary tract infection. We performed a spermogram, hormonal profile, and assessment of leukocytes and cystatin levels in the semen. Results: The ages in the case and control were similar (p = 0.060).The seminal cystatin was significantly different between the case group and control group (41.16 ± 26.59 vs. 79.00 ± 05.68 mg/l, respectively, p < 0.001) and between normospermia and oligospermia (83.50 ± 02.40 vs. 30.34 ± 02.52 mg/l, respectively, p < 0.001). The mean seminal cystatin levels identified by the degrees of oligospermia (severe, moderate, and slim) were similar to each other (p > 0.05) and significantly different (p < 0.05) in relation to normospermia in the case group. The seminal cystatin levels positively correlated (p < 0.05) with sperm motility and sperm density. Conclusion: Seminal cystatin levels are associated with the numerical and motility changes evidenced in the spermogram and may be of help in the initial evaluation of clinical suspicion of sub-fertility and infertility.

Journal

Current UrologyKarger

Published: Jan 1, 2020

Keywords: Chronic kidney disease; Hemodialysis; Cystatin C; Semen; Seminal parameter; Male infertility

There are no references for this article.