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Clinical Significance of the Shwartzman Phenomenon

Clinical Significance of the Shwartzman Phenomenon Hopp cn br o u w e r s , Few Hare Anomalies of the Fundus 133 During the regular control examinations, development of small fluffy spots was observed in the fundus. Shortly after this diagnosis was made, there was an acute exacerbation of the affection accompanied by high tem­ perature, the fundal changes showing a marked increase of activity, especially in the posterior segment of the fundi. There had never been any subjective symptoms of visual disturbance and objective visual changes were not dem­ onstrated either. In the course of the following few weeks, the fundal changes disappeared without leaving traces. Rempt, F. : O phthalm ologica 132, 133, 1956 By F. KEMPT (Delft). This communication may serve as an introduction to the ex­ periments carried out by Dr. Raus in the Ophthalmological Clinic in Rotterdam. The Shwartzman phenomenon in its typical form can be briefly described as follows : Intracutaneous injection of a sterile bacterial filtrate into a rab­ bit produces a simple inflammatory reaction which disappears after a few days. However, if 24 hours later this preliminary in­ jection (P-injection) is followed by an intravenous injection (re­ active or R-injection) of the same filtrate, the animal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Ophthalmologica Karger

Clinical Significance of the Shwartzman Phenomenon

Rempt, F.
Ophthalmologica , Volume 132 (3): 4 – Jan 1, 2010
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Publisher
Karger
Copyright
© 1956 S. Karger AG, Basel
ISSN
0030-3755
eISSN
1423-0267
DOI
10.1159/000302940
Publisher site
See Article on Publisher Site

Abstract

Hopp cn br o u w e r s , Few Hare Anomalies of the Fundus 133 During the regular control examinations, development of small fluffy spots was observed in the fundus. Shortly after this diagnosis was made, there was an acute exacerbation of the affection accompanied by high tem­ perature, the fundal changes showing a marked increase of activity, especially in the posterior segment of the fundi. There had never been any subjective symptoms of visual disturbance and objective visual changes were not dem­ onstrated either. In the course of the following few weeks, the fundal changes disappeared without leaving traces. Rempt, F. : O phthalm ologica 132, 133, 1956 By F. KEMPT (Delft). This communication may serve as an introduction to the ex­ periments carried out by Dr. Raus in the Ophthalmological Clinic in Rotterdam. The Shwartzman phenomenon in its typical form can be briefly described as follows : Intracutaneous injection of a sterile bacterial filtrate into a rab­ bit produces a simple inflammatory reaction which disappears after a few days. However, if 24 hours later this preliminary in­ jection (P-injection) is followed by an intravenous injection (re­ active or R-injection) of the same filtrate, the animal

Journal

Ophthalmologica – Karger

Published: Jan 1, 2010

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