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Angiosarcoma of the Prostate Gland following Brachytherapy for Prostatic Adenocarcinoma

Angiosarcoma of the Prostate Gland following Brachytherapy for Prostatic Adenocarcinoma Prostatic adenocarcinoma is the most common cancer in men, but only a handful of cases of prostatic angiosarcoma have been reported in the literature. Prior radiation therapy for prostatic adenocarcinoma has been hypothesized to be a risk factor for angiosarcoma. The increasing practice of prostate cancer screening and the use of radiation therapy for management of prostatic adenocarcinoma will likely lead to more cases of prostatic angiosarcoma. Diagnosis is made by tissue sampling. Optimal management of these aggressive tumors remains to be defined and outcomes are poor with a high 1-year mortality. Primary care physicians and urologists should be aware of this rare entity and refer these patients to specialist centers where they can be managed by a multidisciplinary team. We report a case of angiosarcoma of the prostate gland diagnosed in a male presenting with lower urinary tract symptoms 5 years after brachytherapy for prostate adenocarcinoma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Urology Karger

Angiosarcoma of the Prostate Gland following Brachytherapy for Prostatic Adenocarcinoma

Current Urology , Volume 8 (2): 4 – Jan 1, 2015

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Publisher
Karger
Copyright
© 2015 S. Karger AG, Basel
ISSN
1661-7649
eISSN
1661-7657
DOI
10.1159/000365700
Publisher site
See Article on Publisher Site

Abstract

Prostatic adenocarcinoma is the most common cancer in men, but only a handful of cases of prostatic angiosarcoma have been reported in the literature. Prior radiation therapy for prostatic adenocarcinoma has been hypothesized to be a risk factor for angiosarcoma. The increasing practice of prostate cancer screening and the use of radiation therapy for management of prostatic adenocarcinoma will likely lead to more cases of prostatic angiosarcoma. Diagnosis is made by tissue sampling. Optimal management of these aggressive tumors remains to be defined and outcomes are poor with a high 1-year mortality. Primary care physicians and urologists should be aware of this rare entity and refer these patients to specialist centers where they can be managed by a multidisciplinary team. We report a case of angiosarcoma of the prostate gland diagnosed in a male presenting with lower urinary tract symptoms 5 years after brachytherapy for prostate adenocarcinoma.

Journal

Current UrologyKarger

Published: Jan 1, 2015

Keywords: Sarcoma; Prostate cancer; Radiation-induced cancer; Prostate biopsy

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