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R. Liu (2013)
Health-promoting components of fruits and vegetables in the diet.Advances in nutrition, 4 3
Zhou Zhou, M. Nair, K. Claycombe (2012)
Synergistic inhibition of interleukin-6 production in adipose stem cells by tart cherry anthocyanins and atorvastatin.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19 10
E. Seymour, Andrew Singer, Ara Kirakosyan, Daniel Urcuyo-Llanes, P. Kaufman, S. Bolling (2008)
Altered hyperlipidemia, hepatic steatosis, and hepatic peroxisome proliferator-activated receptors in rats with intake of tart cherry.Journal of medicinal food, 11 2
F. Blando, C. Gerardi, I. Nicoletti (2004)
Sour Cherry (Prunus cerasus L) Anthocyanins as Ingredients for Functional FoodsJournal of Biomedicine and Biotechnology, 2004
Vanisree Mulabagal, G. Lang, D. Dewitt, Sanjeev Dalavoy, M. Nair (2009)
Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries.Journal of agricultural and food chemistry, 57 4
Haibo Wang, M. Nair, G. Strasburg, Y. Chang, A. Booren, J. Gray, David DeWitt (1999)
Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherriesJournal of natural products, 62 5
N. Asfaw, S. Demissew (1994)
Phytochemical Dictionary: A Handbook of Bioactive Compounds from PlantsEconomic Botany, 48
Chandan Prasad, V. Imrhan, F. Marotta, S. Juma, P. Vijayagopal (2014)
Lifestyle and Advanced Glycation End Products (AGEs) Burden: Its Relevance to Healthy Aging.Aging and disease, 5 3
R. Liu (2003)
Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals.The American journal of clinical nutrition, 78 3 Suppl
P. Bell, D. Gaze, G. Davison, T. George, M. Scotter, G. Howatson (2014)
Montmorency tart cherry (Prunus cerasus L.) concentrate lowers uric acid, independent of plasma cyanidin-3-O-glucosiderutinosideJournal of Functional Foods, 11
K. Kuehl (2012)
Cherry juice targets antioxidant potential and pain relief.Medicine and sport science, 59
Ara Kirakosyan, E. Seymour, D. Llanes, P. Kaufman, S. Bolling (2009)
Chemical profile and antioxidant capacities of tart cherry productsFood Chemistry, 115
Haibo Wang, M. Nair, G. Strasburg, A. Booren, J. Gray (1999)
Antioxidant polyphenols from tart cherries (Prunus cerasus).Journal of agricultural and food chemistry, 47 3
L. Laine, W. White, A. Rostom, M. Hochberg (2008)
COX-2 selective inhibitors in the treatment of osteoarthritis.Seminars in arthritis and rheumatism, 38 3
G. Ferretti, T. Bacchetti, A. Belleggia, D. Neri (2010)
Cherry Antioxidants: From Farm to TableMolecules, 15
T. Traustadóttir, S. Davies, Anthoney Stock, Yali Su, C. Heward, L. Roberts, S. Harman (2009)
Tart cherry juice decreases oxidative stress in healthy older men and women.The Journal of nutrition, 139 10
E. Seymour, Sarah Lewis, Daniel Urcuyo-Llanes, I. Tanone, Ara Kirakosyan, P. Kaufman, S. Bolling (2009)
Regular tart cherry intake alters abdominal adiposity, adipose gene transcription, and inflammation in obesity-prone rats fed a high fat diet.Journal of medicinal food, 12 5
K. Kuehl, E. Perrier, D. Elliot, J. Chesnutt (2010)
Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trialJournal of the International Society of Sports Nutrition, 7
N. Seeram, L. Bourquin, M. Nair (2001)
Degradation products of cyanidin glycosides from tart cherries and their bioactivities.Journal of agricultural and food chemistry, 49 10
J. Tall, N. Seeram, Chengshui Zhao, M. Nair, R. Meyer, S. Raja (2004)
Tart cherry anthocyanins suppress inflammation-induced pain behavior in ratBehavioural Brain Research, 153
N. Schlesinger (2012)
Pilot Studies of Cherry Juice Concentrate for Gout Flare ProphylaxisJournal of Arthritis, 1
Ying-hui He, J. Zhou, Y-S Wang, C. Xiao, Y. Tong, J. Tang, A. Chan, A. Lu (2006)
Anti‐inflammatory and anti‐oxidative effects of cherries on Freund's adjuvant‐induced arthritis in ratsScandinavian Journal of Rheumatology, 35
Dae-Ok Kim, H. Heo, Y. Kim, H. Yang, Chang Lee (2005)
Sweet and sour cherry phenolics and their protective effects on neuronal cells.Journal of agricultural and food chemistry, 53 26
Victoria Johnson, D. Hunter (2014)
The epidemiology of osteoarthritis.Best practice & research. Clinical rheumatology, 28 1
B. Ou, Kristen Bosak, Paula Brickner, Dominic Iezzoni, E. Seymour (2012)
Processed tart cherry products--comparative phytochemical content, in vitro antioxidant capacity and in vitro anti-inflammatory activity.Journal of food science, 77 5
Haibo Wang, M. Nair, G. Strasburg, A. Booren, I. Gray, David DeWitt (2000)
Cyclooxygenase active bioflavonoids from Balaton tart cherry and their structure activity relationships.Phytomedicine : international journal of phytotherapy and phytopharmacology, 7 1
J. Bowtell, D. Sumners, A. Dyer, Patrick Fox, K. Mileva (2011)
Montmorency cherry juice reduces muscle damage caused by intensive strength exercise.Medicine and science in sports and exercise, 43 8
D. Elliot, K. Kuehl, K. Jones, Kristen Dulacki (2010)
Using an Eccentric Exercise-Testing Protocol to Assess the Beneficial Effects of Tart Cherry Juice in Fibromyalgia Patients
P. Bell, I. Walshe, G. Davison, E. Stevenson, G. Howatson (2014)
Montmorency Cherries Reduce the Oxidative Stress and Inflammatory Responses to Repeated Days High-Intensity Stochastic CyclingNutrients, 6
D. Connolly, M. McHugh, O. Padilla-Zakour, L. Carlson, Stephen Sayers (2006)
Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damageBritish Journal of Sports Medicine, 40
G. Howatson, M. McHugh, Jessica Hill, J. Brouner, A. Jewell, K. Someren, Rob Shave, S. Howatson (2010)
Influence of tart cherry juice on indices of recovery following marathon runningScandinavian Journal of Medicine & Science in Sports, 20
L. Blau (1950)
Cherry diet control for gout and arthritis.Texas reports on biology and medicine, 8 3
R. Prior (2003)
Fruits and vegetables in the prevention of cellular oxidative damage.The American journal of clinical nutrition, 78 3 Suppl
H. Schumacher, S. Pullman‐Mooar, S. Gupta, Janet Dinnella, R. Kim, R. Kim, M. McHugh (2013)
Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee.Osteoarthritis and cartilage, 21 8
N. Ducharme, L. Fortier, M. Kraus, S. Hobo, H. Mohammed, M. McHugh, R. Hackett, L. Soderholm, L. Mitchell (2009)
Effect of a tart cherry juice blend on exercise-induced muscle damage in horses.American journal of veterinary research, 70 6
J. Tall, S. Raja (2004)
Dietary Constituents as Novel Therapies for PainThe Clinical Journal of Pain, 20
K. Subbaramaiah, A. Dannenberg (2001)
Resveratrol inhibits the expression of cyclooxygenase-2 in mammary epithelial cells.Advances in experimental medicine and biology, 492
Amitabh Chandra, J. Rana, Yingqin Li (2001)
Separation, identification, quantification, and method validation of anthocyanins in botanical supplement raw materials by HPLC and HPLC-MS.Journal of agricultural and food chemistry, 49 8
S. Burkhardt, D. Tan, L. Manchester, R. Hardeland, R. Reiter (2001)
Detection and quantification of the antioxidant melatonin in Montmorency and Balaton tart cherries (Prunus cerasus).Journal of agricultural and food chemistry, 49 10
H. Wang, M. Nair, G. Strasburg, A. Booren, J. Gray (1999)
Novel antioxidant compounds from tart cherries (Prunus cerasus).Journal of natural products, 62 1
S. Volpe (2014)
Tart Cherry Juice and Inflammatory ResponseAcsm's Health & Fitness Journal, 18
N. Seeram, Momin Ra, M. Nair, L. Bourquin (2001)
Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries.Phytomedicine : international journal of phytotherapy and phytopharmacology, 8 5
Jessica Matchynski, Steven Lowrance, C. Pappas, J. Rossignol, Nicole Puckett, M. Sandstrom, G. Dunbar (2013)
Combinatorial treatment of tart cherry extract and essential fatty acids reduces cognitive impairments and inflammation in the mu-p75 saporin-induced mouse model of Alzheimer's disease.Journal of medicinal food, 16 4
F. Haidari, M. Shahi, S. Keshavarz, M. Rashidi (2009)
Inhibitory Effects of Tart Cherry (Prunus cerasus) Juice on Xanthine Oxidoreductase Activity and its Hypouricemic and Antioxidant Effects on Rats.Malaysian journal of nutrition, 15 1
Yuqing Zhang, T. Neogi, Clara Chen, C. Chaisson, D. Hunter, Hyon Choi (2012)
Cherry consumption and decreased risk of recurrent gout attacks.Arthritis and rheumatism, 64 12
A. Lynn, S. Mathew, C. Moore, J. Russell, E. Robinson, V. Soumpasi, M. Barker (2014)
Effect of a Tart Cherry Juice Supplement on Arterial Stiffness and Inflammation in Healthy Adults: A Randomised Controlled TrialPlant Foods for Human Nutrition, 69
K. Kuehl, D. Elliot (2012)
Efficacy of Tart Cherry Juice to Reduce Inflammation Biomarkers among Women with Inflammatory Osteoarthritis (OA), 1
Background:Tart cherry, rich in bioactive polyphenols, has received attention in the past decade for reported health benefits due to its high polyphenolic content.Objective:To determine whether there is a potential role for tart cherry or its isolated components in amelioration of pain relief in chronic diseases that may affect the elderly.Methods:In vitro and in vivo human and animal studies that utilized tart cherry or extracts of tart cherry compounds to determine an effect on oxidative stress, inflammation, muscle damage, and pain were reviewed and summarized (Table 1).Results:Tart cherry and its isolated compounds have demonstrated antioxidant and anti-inflammatory effects both in vitro and in vivo which may improve self-reported pain. In humans, these include modest improvements in gout flare incidents, and self-reported pain in fibromyalgia, osteoarthritis (OA), and conditions of induced oxidative stress and muscle damage. Beneficial biochemical changes were also reported for inflammatory and oxidative biomarkers such as serum urate, C-reactive protein (CRP), and interleukin-6 (IL-6). However, most studies reported to date have insufficient sample size, treatment duration, and statistical power to draw any firm conclusions.Conclusions:Consumption of tart cherries and their bioactive constituents may be a potential novel therapy for reducing the pain associated with chronic diseases particularly common to an aged population. Larger, more rigorous trials are needed to reach any firm conclusions.
Nutrition and Aging – IOS Press
Published: Jan 1, 2016
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