Access the full text.
Sign up today, get DeepDyve free for 14 days.
Optimization of X-ray microplanar beam radiation therapy for deep-seated tumors
K. Shinohara, H. Nakano, N. Miyazaki, M. Tago, R. Kodama (2004)
Effects of single-pulse (< or = 1 ps) X-rays from laser-produced plasmas on mammalian cells.Journal of radiation research, 45 4
D. Anschel, A. Bravin, P. Romanelli (2011)
Microbeam radiosurgery using synchrotron-generated submillimetric beams: a new tool for the treatment of brain disordersNeurosurgical Review, 34
K. Sakaue, M. Washio, S. Araki, M. Fukuda, Y. Higashi, Y. Honda, T. Omori, T. Taniguchi, N. Terunuma, J. Urakawa, N. Sasao (2009)
Observation of pulsed x-ray trains produced by laser-electron Compton scatterings.The Review of scientific instruments, 80 12
A. Bouchet, B. Lemasson, G. Duc, C. Maisin, E. Bräuer‐Krisch, E. Siegbahn, L. Renaud, E. Khalil, C. Rémy, Cathy Poillot, A. Bravin, J. Laissue, E. Barbier, R. Serduc (2010)
Preferential effect of synchrotron microbeam radiation therapy on intracerebral 9L gliosarcoma vascular networks.International journal of radiation oncology, biology, physics, 78 5
F. Dilmanian, G. Morris, G. Duc, X. Huang, B. Ren, T. Bacarian, J. Allen, J. Kalef-Ezra, I. Orion, E. Rosen, T. Sandhu, P. Sathé, X. Wu, Z. Zhong, H. Shivaprasad (2001)
Response of avian embryonic brain to spatially segmented x-ray microbeams.Cellular and molecular biology, 47 3
J. Laissue, N. Lyubimova, H. Wagner, D. Archer, D. Slatkin, M. Michiel, C. Némoz, M. Renier, E. Brauer, P. Spanne, Jan-O. Gebbers, K. Dixon, H. Blattmann (1999)
Microbeam radiation therapy, 3770
R. Serduc, A. Bouchet, E. Bräuer‐Krisch, J. Laissue, J. Spiga, S. Sarun, A. Bravin, C. Fonta, L. Renaud, J. Boutonnat, E. Siegbahn, F. Estève, G. Duc (2009)
Synchrotron microbeam radiation therapy for rat brain tumor palliation—influence of the microbeam width at constant valley dosePhysics in Medicine & Biology, 54
E. Bräuer‐Krisch, R. Serduc, E. Siegbahn, G. Duc, Y. Prezado, A. Bravin, H. Blattmann, J. Laissue (2010)
Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue.Mutation research, 704 1-3
J. Laissue, Gabrielle Geiser, P. Spanne, F. Dilmanian, J. Gebbers, M. Geiser, Xiao‐Ye Wu, M. Makar, P. Micca, M. Nawrocky, D. Joel, D. Slatkin (1998)
Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron‐wiggler‐generated X raysInternational Journal of Cancer, 78
M. Labrousse, G. Hossu, G. Hossu, G. Calmon, G. Calmon, A. Chays, J. Felblinger, J. Felblinger, M. Braun (2012)
In vivo characterization of the vestibulo-cochlear nerve motion by MRINeuroImage, 59
M. Miura, H. Blattmann, E. Bräuer‐Krisch, A. Bravin, A. Hanson, M. Nawrocky, P. Micca, D. Slatkin, J. Laissue (2006)
Radiosurgical palliation of aggressive murine SCCVII squamous cell carcinomas using synchrotron-generated X-ray microbeams.The British journal of radiology, 79 937
S. Cipiccia, Mohammad Islam, B. Ersfeld, R. Shanks, E. Brunetti, G. Vieux, Xue Yang, R. Issac, S. Wiggins, G. Welsh, M. Anania, D. Maneuski, R. Montgomery, Gary Smith, M. Hoek, D. Hamilton, N. Lemos, D. Symes, P. Rajeev, V. Shea, João Dias, D. Jaroszynski (2011)
Gamma-rays from harmonically resonant betatron oscillations in a plasma wakeNature Physics, 7
P. Schweizer, P. Spanne, M. Michiel, U. Jauch, H. Blattmann, J. Laissue (2000)
Tissue lesions caused by microplanar beams of synchrotron-generated X-rays in Drosophila melanogaster.International journal of radiation biology, 76 4
W. Straile, H. Chase (1963)
The use of elongate microbeams of x-rays for simulating the effects of cosmic rays on tissues: a study of wound healing and hair follicle regeneration.Radiation research, 18
Malcolm Cooper (2011)
Synchrotron Radiation
E. Amato, A. Italiano, S. Leotta, S. Pergolizzi, L. Torrisi (2013)
Monte Carlo study of the dose enhancement effect of gold nanoparticles during X-ray therapies and evaluation of the anti-angiogenic effect on tumour capillary vessels.Journal of X-ray science and technology, 21 2
J. Crosbie, Robin Anderson, K. Rothkamm, Christina Restall, L. Cann, Saleela Ruwanpura, S. Meachem, N. Yagi, I. Svalbe, R. Lewis, B. Williams, P. Rogers (2010)
Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues.International journal of radiation oncology, biology, physics, 77 3
N. Nariyama, T. Ohigashi, K. Umetani, K. Shinohara, Hiroki Tanaka, A. Maruhashi, G. Kashino, A. Kurihara, T. Kondob, M. Fukumoto, K. Ono (2009)
Spectromicroscopic film dosimetry for high-energy microbeam from synchrotron radiation.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 67 1
D. Slatkin, P. Spanne, F. Dilmanian, Jan-O. Gebbers, J. Laissue (1995)
Subacute neuropathological effects of microplanar beams of x-rays from a synchrotron wiggler.Proceedings of the National Academy of Sciences of the United States of America, 92 19
R. Kuroda, H. Toyokawa, M. Yasumoto, H. Ikeura-Sekiguchi, M. Koike, K. Yamada, T. Yanagida, T. Nakajyo, F. Sakai, K. Mori (2011)
Quasi-monochromatic hard X-ray source via laser Compton scattering and its applicationNuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment, 637
F. Dilmanian, G. Morris, N. Zhong, T. Bacarian, J. Hainfeld, J. Kalef-Ezra, L. Brewington, J. Tammam, E. Rosen (2003)
Murine EMT-6 Carcinoma: High Therapeutic Efficacy of Microbeam Radiation Therapy, 159
E. Schültke, B. Juurlink, K. Ataelmannan, J. Laissue, H. Blattmann, E. Bräuer‐Krisch, A. Bravin, J. Minczewska, J. Crosbie, Hadi Taherian, E. Frangou, Tomasz Wysokinsky, L. Chapman, R. Griebel, D. Fourney (2008)
Memory and survival after microbeam radiation therapy.European journal of radiology, 68 3 Suppl
R. Serduc, Pascale Vérant, J. Vial, R. Farion, Linda Rocas, C. Rémy, Taoufik Fadlallah, E. Brauer, A. Bravin, J. Laissue, H. Blattmann, B. Sanden (2006)
In vivo two-photon microscopy study of short-term effects of microbeam irradiation on normal mouse brain microvasculature.International journal of radiation oncology, biology, physics, 64 5
H. Smilowitz, H. Blattmann, E. Bräuer‐Krisch, A. Bravin, M. Michiel, J. Gebbers, A. Hanson, N. Lyubimova, D. Slatkin, D. Slatkin, J. Štěpánek, J. Laissue (2006)
Synergy of gene-mediated immunoprophylaxis and microbeam radiation therapy for advanced intracerebral rat 9L gliosarcomasJournal of Neuro-Oncology, 78
(2013)
Experimental study for cancer treatment using synchrotron radiation
Y. Prezado, S. Thengumpallil, M. Renier, A. Bravin (2009)
X-ray energy optimization in minibeam radiation therapy.Medical physics, 36 11
W. Zeman, H. Curtis, C. Baker (1961)
Histopathologic effect of high-energy-particle microbeams on the visual cortex of the mouse brain.Radiation research, 15
L. Squire, R. Novelline (1997)
Fundamentals of Radiology
J. Laissue, H. Blattmann, M. Michiel, D. Slatkin, N. Lyubimova, R. Guzman, W. Zimmermann, S. Birrer, T. Bley, P. Kircher, R. Stettler, R. Fatzer, A. Jaggy, H. Smilowitz, E. Brauer, A. Bravin, G. Duc, C. Némoz, M. Renier, W. Thomlinson, J. Štěpánek, H. Wagner (2001)
Weanling piglet cerebellum: a surrogate for tolerance to MRT (microbeam radiation therapy) in pediatric neuro-oncology, 4508
N. Zhong, G. Morris, T. Bacarian, E. Rosen, F. Dilmanian (2003)
Response of Rat Skin to High-Dose Unidirectional X-Ray Microbeams: A Histological Study, 160
(2008)
Principles and applications of compact laserplasma accelerators
B. Sanden, E. Bräuer‐Krisch, E. Siegbahn, C. Ricard, J. Vial, J. Laissue (2010)
Tolerance of arteries to microplanar X-ray beams.International journal of radiation oncology, biology, physics, 77 5
F. Dilmanian, Terry Button, G. Duc, N. Zhong, Louis Peña, Jennifer Smith, Steve Martinez, T. Bacarian, J. Tammam, B. Ren, Peter Farmer, J. Kalef-Ezra, P. Micca, M. Nawrocky, James Niederer, F. Recksiek, A. Fuchs, Eliot Rosen (2002)
Response of rat intracranial 9L gliosarcoma to microbeam radiation therapy.Neuro-oncology, 4 1
R. Serduc, E. Bräuer‐Krisch, A. Bouchet, L. Renaud, T. Brochard, A. Bravin, J. Laissue, G. Duc (2009)
First trial of spatial and temporal fractionations of the delivered dose using synchrotron microbeam radiation therapy.Journal of synchrotron radiation, 16 Pt 4
Pierrick Régnard, G. Duc, E. Bräuer‐Krisch, I. Troprès, E. Siegbahn, Audrey Kusak, Charlotte Clair, Hélène Bernard, D. Dalléry, J. Laissue, A. Bravin (2008)
Irradiation of intracerebral 9L gliosarcoma by a single array of microplanar x-ray beams from a synchrotron: balance between curing and sparingPhysics in Medicine & Biology, 53
K. Sakaue, T. Aoki, M. Washio, S. Araki, M. Fukuda, N. Terunuma, J. Urakawa (2012)
First refraction contrast imaging via Laser-Compton Scattering X-ray at KEK, 1466
S. Sabatasso, J. Laissue, R. Hlushchuk, W. Graber, A. Bravin, E. Bräuer‐Krisch, S. Corde, H. Blattmann, G. Gruber, V. Djonov (2011)
Microbeam radiation-induced tissue damage depends on the stage of vascular maturation.International journal of radiation oncology, biology, physics, 80 5
(2012)
Chalcone JAI-51 improves efficacy of synchrotron microbeam radiation therapy of brain tumors
A Monte Carlo simulation was applied to study the energy dependence on the transverse dose distribution of microplanar beam radiation therapy (MRT) for deep-seated tumors. The distribution was found to be the peak (in-beam) dose and the decay from the edge of the beam down to the valley. The area below the same valley dose level (valley region) was decreased with the increase in the energy of X-rays at the same beam separation. To optimize the MRT, we made the following two assumptions: the therapeutic gain may be attributed to the efficient recovery of normal tissue caused by the beam separation; and a key factor for the efficient recovery of normal tissue depends on the area size of the valley region. Based on these assumptions and the results of the simulated dose distribution, we concluded that the optimum X-ray energy was in the range of 100–300 keV depending on the effective peak dose to the target tumors and/or tolerable surface dose. In addition, we proposed parameters to be studied for the optimization of MRT to deep-seated tumors.
Journal of X-Ray Science and Technology – IOS Press
Published: Jan 1, 2014
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.