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- Publisher
- IOS Press
- Copyright
- Copyright © 2018 IOS Press and the authors. All rights reserved
- ISSN
- 1093-2607
- eISSN
- 1875-869X
- DOI
- 10.3233/HAB-170319
- pmid
- 28505966
- Publisher site
- See Article on Publisher Site
Abstract
Despite its relevance to many biomedical fields, relatively little effort has been put into a comprehensible quantitative description of the effect of reaction temperature on the interaction between antigens and their antibodies. In this article, a novel, straightforward mathematical model is proposed, which aims to describe the effect of temperature on antigen-antibody kinetics. The model proposed in this article could hopefully provide clinicians, immunologists, and biochemists with an improved insight into the kinetic effect of fluctuations in reaction temperature on antigen-antibody-dependent processes and therefore into the kinetics of the humoral adaptive immune response.
Journal
Human Antibodies – IOS Press
Published: Jan 1, 2019