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- Publisher
- IOS Press
- Copyright
- Copyright © 2017 IOS Press and the authors. All rights reserved
- ISSN
- 0895-3996
- eISSN
- 1095-9114
- DOI
- 10.3233/XST-16184
- pmid
- 27911351
- Publisher site
- See Article on Publisher Site
Abstract
Grating-based differential phase contrast (DPC) imaging enables the use of a hospital-grade X-ray tube, but compromises the image quality due to insufficiently coherent illumination. In this research, a bench-top DPC cone beam CT (DPC-CBCT) was systematically evaluated and compared with the traditional attenuation-based CBCT in terms of contrast to noise ratio, noise property, and contrast resolution through phantom studies. In order to evaluate DPC-CBCT for soft tissue imaging, breast specimen and small animal studies were carried out. Phantom studies indicate that phase image has lower-frequency noise, higher CNR, and improved contrast resolution. However, phase image quality was degraded in soft tissue imaging due to coherence loss caused by small-angle scattering. Hence dark-field imaging was introduced to quantitatively investigate small-angle scattering caused by an object. Experimental results indicate that inhomogeneous objects affect phase contrast imaging, phase image is more sensitive to noise, and its performance is material dependent. Dark-field imaging could also be used to locate and reduce phase image noise and artifact caused by small-angle scattering.
Journal
Journal of X-Ray Science and Technology – IOS Press
Published: Jan 1, 2017