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Detection of glucose concentration using a surface plasmon resonance biosensor based on barium titanate layers and molybdenum disulphide sheets

Detection of glucose concentration using a surface plasmon resonance biosensor based on barium... Diabetes is rapidly becoming a serious and life-threatening disease. It affects 415 million persons worldwide and is a leading cause of death among those aged 20 to 59. It is essential to develop a rapid-detection, accurate and sensitive glucose detector. In this work, a biosensor based on surface plasmon resonance (SPR) is proposed theoretically for the detection of glucose concentration. To realize higher sensitivity, the proposed SPR sensor contains a barium titanate layer placed between the metal (Ag) thin film and the molybdenum disulphide layer. Barium titanate material shows notable dielectric properties, such as low loss and a high index of refraction. It is expected to give a large shift in the resonance angle caused by a tiny change in the analyte refractive index. By optimizing the thicknesses of barium titanate and Ag and the number of molybdenum disulphide layers, the proposed biosensor can exhibit an ultra-high sensitivity of 307.36 deg RIU−1. The extremely high sensitivity makes the proposed SPR-based biosensor encouraging to be used in many fields of biosensing. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Physica Scripta IOP Publishing

Detection of glucose concentration using a surface plasmon resonance biosensor based on barium titanate layers and molybdenum disulphide sheets

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Publisher
IOP Publishing
Copyright
© 2022 IOP Publishing Ltd
ISSN
0031-8949
eISSN
1402-4896
DOI
10.1088/1402-4896/ac68ad
Publisher site
See Article on Publisher Site

Abstract

Diabetes is rapidly becoming a serious and life-threatening disease. It affects 415 million persons worldwide and is a leading cause of death among those aged 20 to 59. It is essential to develop a rapid-detection, accurate and sensitive glucose detector. In this work, a biosensor based on surface plasmon resonance (SPR) is proposed theoretically for the detection of glucose concentration. To realize higher sensitivity, the proposed SPR sensor contains a barium titanate layer placed between the metal (Ag) thin film and the molybdenum disulphide layer. Barium titanate material shows notable dielectric properties, such as low loss and a high index of refraction. It is expected to give a large shift in the resonance angle caused by a tiny change in the analyte refractive index. By optimizing the thicknesses of barium titanate and Ag and the number of molybdenum disulphide layers, the proposed biosensor can exhibit an ultra-high sensitivity of 307.36 deg RIU−1. The extremely high sensitivity makes the proposed SPR-based biosensor encouraging to be used in many fields of biosensing.

Journal

Physica ScriptaIOP Publishing

Published: Jun 1, 2022

Keywords: glucose concentration; surface plasmon resonance; sensor; barium titanate; molybdenum disulphide

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