Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Nuclear morphometric study of prostatic atrophy

Nuclear morphometric study of prostatic atrophy Abstract The prostatic atrophy is a lesion with small glands that can mimic adenocarcinoma, commonly diagnosed in the elderly and whose preneoplastic role is controversial. Over time several classifications have been developed for this lesions according to its architectural and cellular aspects. Materials and Methods: Aim of the study is morphometrically assessment of epithelial component nuclei in prostatic atrophy. We evaluated parameters represented by nuclear area (NA), nuclear perimeter P (μm) Elongation factor (E), average diameter (DEQ), maximum diameter (Dmax), Minim diameter (Dmin). The control group was represented by adenomatous hyperplasia component of benign hyperplasia of the prostate. Results: Morphometric analysis revealed significantly higher values of nuclear parameters in atrophy compared with adenomatous component in controls (p <0.05) which can signify nucleomegaly and a potential preneoplastic role. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ARS Medica Tomitana de Gruyter

Nuclear morphometric study of prostatic atrophy

Loading next page...
 
/lp/de-gruyter/nuclear-morphometric-study-of-prostatic-atrophy-V80XXTLs8b
Publisher
de Gruyter
Copyright
Copyright © 2015 by the
ISSN
1841-4036
eISSN
1841-4036
DOI
10.1515/arsm-2015-0028
Publisher site
See Article on Publisher Site

Abstract

Abstract The prostatic atrophy is a lesion with small glands that can mimic adenocarcinoma, commonly diagnosed in the elderly and whose preneoplastic role is controversial. Over time several classifications have been developed for this lesions according to its architectural and cellular aspects. Materials and Methods: Aim of the study is morphometrically assessment of epithelial component nuclei in prostatic atrophy. We evaluated parameters represented by nuclear area (NA), nuclear perimeter P (μm) Elongation factor (E), average diameter (DEQ), maximum diameter (Dmax), Minim diameter (Dmin). The control group was represented by adenomatous hyperplasia component of benign hyperplasia of the prostate. Results: Morphometric analysis revealed significantly higher values of nuclear parameters in atrophy compared with adenomatous component in controls (p <0.05) which can signify nucleomegaly and a potential preneoplastic role.

Journal

ARS Medica Tomitanade Gruyter

Published: May 1, 2015

References