Access the full text.
Sign up today, get DeepDyve free for 14 days.
Guyue Cheng, H. Hao, Menghong Dai, Zhenli Liu, Zonghui Yuan (2013)
Antibacterial action of quinolones: from target to network.European journal of medicinal chemistry, 66
Esra’a Abu-Sheaib, Jalal Zahra, M. El-Abadelah, W. Voelter (2008)
Heterocycles [h]-Fused onto 4-Oxoquinoline-3-carboxylic Acid, V [1]. Synthesis and Antibacterial Activity of Some New 2,3-Disubstituted 7-Oxo-7,10-dihydropyrido[2,3-f]quinoxaline-8-carboxylic Acids and EstersZeitschrift für Naturforschung B, 63
Jalal Zahra, Hala Al‐Jaber, M. El-Abadelah, Mohammed Abadleh, Saudia Arabia (2011)
HETEROCYCLES (H)-FUSED TO 4-OXOQUINOLINE-3-CARBOXYLIC ACID. PART IX. 1 SYNTHESIS OF 2,6-DIOXOTETRAHYDRO-1H- PYRROLO(3,2-H)QUINOLINE-7-CARBOXYLIC ACIDHeterocycles, 83
Salah Al-Trawneh, Jalal Zahra, M. Kamal, M. El-Abadelah, F. Zani, M. Incerti, A. Cavazzoni, R. Alfieri, P. Petronini, P. Vicini (2010)
Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents.Bioorganic & medicinal chemistry, 18 16
Batool Farrayeh, M. El-Abadelah, Jalal Zahra, S. Haddad, Wolfgang Voelte (2013)
Heterocycles [h]-Fused onto 4-Oxoquinoline-3-carboxylic Acid. Part X [1]. Synthesis and X-Ray Structure of a Model 4- Oxo[1,4]benzoxazepino[2,3-h]quinoline-3-carboxylic EsterZeitschrift für Naturforschung B, 68
AbstractA series of 2-hetaryl-4-fluoro-9-cyclopropyl-6-oxo-1H-imidazo[4,5-h]quinoline-7-carboxylic esters (3a–f) and their corresponding acids 4a–f have been prepared via microwave-assisted cyclocondensation reaction with some hetarene carboxaldehydes. The structures for these new esters and acids are based on spectral (IR, MS, and NMR) data. The in vitro antimicrobial assay of 4a–f hetaryl derivatives, their aryl analogues 1d–g, and the imidazo-unsubstituted acid 1a showed that all of these tricyclic heterocycles possess a good level of antibacterial activity. Among them, compound 1a exhibited the highest effect against both, Gram-positive (minimum inhibitory concentrations [MICs] 0.15–3.0 μg mL–1) and Gram-negative bacteria (MICs 0.7–3.0 μg mL–1). An excellent activity was recorded also for the halo-phenyl derivatives 1f,g and for the furan derivatives 4e,f, especially toward Gram-positive strains and Bacillus subtilis and Haemophilus influenzae, respectively.
Zeitschrift für Naturforschung B – de Gruyter
Published: Jan 1, 2016
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.