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B. Galer, M. Rowbotham, J. Perander, Allison Devers, Erika Friedman (2000)
Topical diclofenac patch relieves minor sports injury pain: results of a multicenter controlled clinical trial.Journal of pain and symptom management, 19 4
T. Loftsson, Már Másson (2001)
Cyclodextrins in topical drug formulations: theory and practice.International journal of pharmaceutics, 225 1-2
J. Szejtli (1998)
Introduction and General Overview of Cyclodextrin ChemistryChemInform, 29
Thandavamoorthy Subbiah, G. Bhat, R. Tock, S. Parameswaran, S. Ramkumar (2005)
Electrospinning of nanofibersJournal of Applied Polymer Science, 96
E. Martin, De Valle, E. Del, Valle (2004)
Cyclodextrins and their uses: a reviewProcess Biochemistry, 39
R. MachÃn, J. Isasi, I. Vélaz (2012)
β-Cyclodextrin hydrogels as potential drug delivery systemsCarbohydrate Polymers, 87
C. Fernandes, F. Veiga (2002)
Effect of the hydrophobic nature of triacetyl-beta-cyclodextrin on the complexation with nicardipine hydrochloride: physicochemical and dissolution properties of the kneaded and spray-dried complexes.Chemical & pharmaceutical bulletin, 50 12
K. Adibkia, M. Barzegar-Jalali, H. Maheri-Esfanjani, S. Ghanbarzadeh, J. Shokri, A. Sabzevari, Y. Javadzadeh (2013)
Physicochemical characterization of naproxen solid dispersions prepared via spray drying technologyPowder Technology, 246
Abhijit Banik, Paramartha Gogoi, M. Saikia (2012)
Interaction of naproxen with β-cyclodextrin and its derivatives/polymer: experimental and molecular modeling studiesJournal of Inclusion Phenomena and Macrocyclic Chemistry, 72
M. Arco, Sonia Gutiérrez, Cristina MartÃn, V. Rives, J. Rocha (2004)
Synthesis and characterization of layered double hydroxides (LDH) intercalated with non-steroidal anti-inflammatory drugs (NSAID)Journal of Solid State Chemistry, 177
P. Taepaiboon, U. Rungsardthong, P. Supaphol (2006)
Drug-loaded electrospun mats of poly(vinyl alcohol) fibres and their release characteristics of four model drugsNanotechnology, 17
H. Ammar, M. Ghorab, A. Mahmoud, T. Makram, S. Noshi (2012)
Topical liquid crystalline gel containing lornoxicam/cyclodextrin complexJournal of Inclusion Phenomena and Macrocyclic Chemistry, 73
Tayade Pralhad, K. Rajendrakumar (2004)
Study of freeze-dried quercetin-cyclodextrin binary systems by DSC, FT-IR, X-ray diffraction and SEM analysis.Journal of pharmaceutical and biomedical analysis, 34 2
E. Kumbasar, Ç. Akduman, A. Çay (2014)
Effects of β-cyclodextrin on selected properties of electrospun thermoplastic polyurethane nanofibres.Carbohydrate polymers, 104
Zong-Zhu Piao, Mi-Kyung Lee, Beom-Jin Lee (2008)
Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex.International journal of pharmaceutics, 350 1-2
E. Kenawy, F. Abdel-Hay, M. El-Newehy, G. Wnek (2007)
Controlled release of ketoprofen from electrospun poly(vinyl alcohol) nanofibersMaterials Science and Engineering A-structural Materials Properties Microstructure and Processing, 459
Min Wei, Shuxian Shi, J. Wang, Yong Li, X. Duan (2004)
Studies on the intercalation of naproxen into layered double hydroxide and its thermal decomposition by in situ FT-IR and in situ HT-XRDJournal of Solid State Chemistry, 177
Thorsteinn PhD, Jon PhD (1998)
Cyclodextrins: new drug delivery systems in dermatologyInternational Journal of Dermatology, 37
Heather Grandelli, B. Stickle, A. Whittington, E. Kiran (2013)
Inclusion complex formation of β-cyclodextrin and Naproxen: a study on exothermic complex formation by differential scanning calorimetryJournal of Inclusion Phenomena and Macrocyclic Chemistry, 77
Y. Javadzadeh, F. Ahadi, S. Davaran, G. Mohammadi, A. Sabzevari, K. Adibkia (2010)
Preparation and physicochemical characterization of naproxen-PLGA nanoparticles.Colloids and surfaces. B, Biointerfaces, 81 2
M. Brewster, T. Loftsson (2007)
Cyclodextrins as pharmaceutical solubilizers.Advanced drug delivery reviews, 59 7
P. Mura, M. Faucci, Bettinetti Gp (2001)
The influence of polyvinylpyrrolidone on naproxen complexation with hydroxypropyl-beta-cyclodextrin.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 13 2
S. Junco, T. Casimiro, Nuno Ribeiro, M. Ponte, H. Marques (2002)
A Comparative Study of Naproxen – Beta Cyclodextrin Complexes Prepared by Conventional Methods and Using Supercritical Carbon DioxideJournal of inclusion phenomena and macrocyclic chemistry, 44
Abstract Incorporation of cyclodextrins (CDs) into electrospun nanofibrous materials can be considered as potential candidates for functional medical textile applications. Naproxen (NAP) is a type of non-steroidal anti-inflammatory drug commonly administered for the treatment of pain, inflammation and fever. Drug-inclusion complex formation with CDs is an approach to improve the aqueous solubility via molecular encapsulation of the drug within the cavity of the more soluble CD molecule. In this study, NAP or different NAP-CD inclusion complexes loaded nanofibres were successfully produced through electrospinning and characterised. The inclusion complex loaded mats exhibited significantly faster release profiles than NAP-loaded thermoplastic polyurethane (TPU) mats. Overall, NAP-inclusion complex loaded TPU electrospun nanofibres could be used as drug delivery systems for acute pain treatments since they possess a highly porous structure that can release the drug immediately.
Autex Research Journal – de Gruyter
Published: Dec 1, 2014
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