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Development of an in-vivo sensor for monitoring of water content in skin

Development of an in-vivo sensor for monitoring of water content in skin Abstract A change in the water distribution of the human body, such as water retention in the skin, can be a symptom of a pathological condition including heart failure. Therefore, a sensor for the non-invasive quantification of the water content of the skin could be useful where continuous monitoring of patients is required to detect and avoid life threatening conditions. As water is a major absorber of tissue in the near-infrared wavelength range, the water content can be determined based on reflectance measurements. Measuring the diffuse reflectance at multiple distances from the point of illumination allows the determination of absorption in scattering media such as skin. The aim of this project was to develop a small and portable sensor based on light emitting diodes and photodiodes. Evaluation of the first functional sensor design has showed that the water content of tissue phantoms can be predicted with a prediction error of 1%. Further developments towards a sensor that can be applied in a future field study are ongoing. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Photonics & Lasers in Medicine de Gruyter

Development of an in-vivo sensor for monitoring of water content in skin

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Publisher
de Gruyter
Copyright
Copyright © 2015 by the
ISSN
2193-0635
eISSN
2193-0643
DOI
10.1515/plm-2014-0046
Publisher site
See Article on Publisher Site

Abstract

Abstract A change in the water distribution of the human body, such as water retention in the skin, can be a symptom of a pathological condition including heart failure. Therefore, a sensor for the non-invasive quantification of the water content of the skin could be useful where continuous monitoring of patients is required to detect and avoid life threatening conditions. As water is a major absorber of tissue in the near-infrared wavelength range, the water content can be determined based on reflectance measurements. Measuring the diffuse reflectance at multiple distances from the point of illumination allows the determination of absorption in scattering media such as skin. The aim of this project was to develop a small and portable sensor based on light emitting diodes and photodiodes. Evaluation of the first functional sensor design has showed that the water content of tissue phantoms can be predicted with a prediction error of 1%. Further developments towards a sensor that can be applied in a future field study are ongoing.

Journal

Photonics & Lasers in Medicine – de Gruyter

Published: May 1, 2015

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