Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Dental considerations in a patient with haemophilia

Dental considerations in a patient with haemophilia AbstractHaemophilia is a rare blood clotting disorder, characteristic features of which include extemporaneous and post-traumatic subcutaneous bleeding and mucosal haemorrhages. Genetic deficiency of coagulation factor VIII results in haemophilia A, while deficiency of factor IX leads to haemophilia B. The most common treatment for haemophilia A is administration of recombinant or plasma-derived factor VIII concentrate, to raise the levels of the deficient factor VIII. Tranexamic acid is also used as an anti-fibrinolytic agent that inhibits plasminogen activators present in oral secretion and stabilises the clot. Administration of factor IX is required in haemophilia B. Treatment leads to increased longevity and quality of life for patients. Dental conditions and treatments are more complicated and uncertain in patients with haemophilia due to bleeding risk, thus restorative dental care is of paramount importance for those with haemophilia. The fear of bleeding during treatment procedures is the primary cause of lack of proper dental care for people with haemophilia in countries with limited health care resources. This case report highlights the significance of clinical examination and investigation, and the importance of proper interaction between a haematologist and the periodontist for correct multidisciplinary and uneventful management of periodontal health of a patient with haemophilia. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Haemophilia Practice de Gruyter

Dental considerations in a patient with haemophilia

Download PDF
4 pages

Loading next page...
 
/lp/de-gruyter/dental-considerations-in-a-patient-with-haemophilia-NciK680iF9
Publisher
de Gruyter
Copyright
© 2016 Chandra Khyati, Mavinakote Gowda Triveni, Rini Gopal, AB Tarunkumar, Suresh Hanagavadi, Dhoom Singh Mehta, published by Sciendo
eISSN
2055-3390
DOI
10.17225/jhp00070
Publisher site
See Article on Publisher Site

Abstract

AbstractHaemophilia is a rare blood clotting disorder, characteristic features of which include extemporaneous and post-traumatic subcutaneous bleeding and mucosal haemorrhages. Genetic deficiency of coagulation factor VIII results in haemophilia A, while deficiency of factor IX leads to haemophilia B. The most common treatment for haemophilia A is administration of recombinant or plasma-derived factor VIII concentrate, to raise the levels of the deficient factor VIII. Tranexamic acid is also used as an anti-fibrinolytic agent that inhibits plasminogen activators present in oral secretion and stabilises the clot. Administration of factor IX is required in haemophilia B. Treatment leads to increased longevity and quality of life for patients. Dental conditions and treatments are more complicated and uncertain in patients with haemophilia due to bleeding risk, thus restorative dental care is of paramount importance for those with haemophilia. The fear of bleeding during treatment procedures is the primary cause of lack of proper dental care for people with haemophilia in countries with limited health care resources. This case report highlights the significance of clinical examination and investigation, and the importance of proper interaction between a haematologist and the periodontist for correct multidisciplinary and uneventful management of periodontal health of a patient with haemophilia.

Journal

The Journal of Haemophilia Practice – de Gruyter

Published: Jan 1, 2016

References

  • Induction of immune tolerance in patients with hemophilia A and inhibitors treated with porcine VIIIC by home therapy
  • Fibrinolytic activity in periodontal disease. The relationship between fibrinolytic activity and severity of periodontal disease
  • Guidance on the dental management of patients with haemophilia and congenital bleeding disorders
  • Immune Tolerance Study Group (ITSG). Immune tolerance in hemophilia with factor VIII inhibitors: predictors of success
  • Specialty dentistry for the hemophiliac: is there a protocol in place?
  • Rehabilitation of a hemophiliac with implants: a medical perspective and case report
  • Fibrinolytic activity in periodontal disease. The relationship between fibrinolytic activity and severity of periodontal disease
  • Hemophilia and oral health
  • Bleeding disorders of importance in dental care and related patient management
  • Dental management considerations for the patient with an acquired coagulopathy. Part 2: Coagulopathies from drugs
  • Dental management considerations for the patient with an acquired coagulopathy. Part 2: Coagulopathies from drugs
  • Treatment Guidelines Working Group. The World Federation of Hemophilia. Guidelines for the management of hemophilia
  • Immune Tolerance Study Group (ITSG). Immune tolerance in hemophilia with factor VIII inhibitors: predictors of success
  • Induction of immune tolerance in patients with hemophilia A and inhibitors treated with porcine VIIIC by home therapy
  • Bleeding disorders and periodontology
  • Management of traumatic oral-facial injury in the hemophiliac patient with inhibitor: case report
  • Rehabilitation of a hemophiliac with implants: a medical perspective and case report
  • Bleeding disorders of importance in dental care and related patient management
  • Dental procedures in adult patients with hereditary bleeding disorders: 10 years experience in three Italian Hemophilia Centers
  • Treatment Guidelines Working Group. The World Federation of Hemophilia. Guidelines for the management of hemophilia
  • Guidance on the dental management of patients with haemophilia and congenital bleeding disorders
  • Hemophilia and oral health
  • Induction of immune tolerance in patients with hemophilia A and inhibitors
  • Induction of immune tolerance in patients with hemophilia A and inhibitors
  • Comprehensive treatment of periodontitis in patients with von Willebrand disease
  • Bleeding disorders and periodontology
  • Comprehensive treatment of periodontitis in patients with von Willebrand disease
  • Dental procedures in adult patients with hereditary bleeding disorders: 10 years experience in three Italian Hemophilia Centers
  • Management of traumatic oral-facial injury in the hemophiliac patient with inhibitor: case report
  • Specialty dentistry for the hemophiliac: is there a protocol in place?