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Delirium Risk Factors in Elderly Patients Suffering from Femoral Neck Fractures

Delirium Risk Factors in Elderly Patients Suffering from Femoral Neck Fractures References1. Saxena S. and Lawley D. Delirium in the elderly: a clinical review. Postgrad. Med. J. 85, 2009; 405–13. https://doi.org/10.1136/pgmj.2008.0720252. Tucker GJ. The diagnosis of delirium and DSM-IV. Dement GeriatrCognDisord, 1999; 10:359-63. https://doi.org/10.1159/0000171713. Siddiqi N, House AO and Holmes JD. Occurrence and outcome of delirium in medical in-patients: a systematic literature review. Age Ageing 35, 2006; 350–64. https://doi.org/10.1093/ageing/afl0054. Theocharis Chr. Kyziridis. Post-operative delirium after hip fracture treatment: a review of the current literature, GMS Psycho-Social-Medicine 2006, 3: doc 01 http://www.egms.de/en/journals/psm/2006-3/psm000021.shtml5. Angela J, Bruce L, Craig W. Ritchie et al. The incidence of delirium associated with orthopedic surgery: a meta-analytic review. International Psycho-geriatrics 2007, 19: 197–214. https://doi.org/10.1017/S104161020600425X6. Ruggiero C, Bonamassa L, Pelini L et al. Early post-surgical cognitive dysfunction is a risk factor for mortality among hip fracture hospitalized older persons. OsteoporosInt 2017, 28:667–75. https://doi.org/10.1007/s00198-016-3784-37. Dubljanin Raspopovic E, MarkovicDenic L, Marinkovic Jet al. Early mortality after hip fracture: what matters? Psychogeriatrics 2014,15:95–101. https://doi.org/10.1111/psyg.12076Fliss8. Kat MG, de Jonghe JF, Vreeswijk Ret al. Mortality associated with delirium after hip-surgery: a 2-year follow-up study. Age and Ageing 2011, 40:312–18. https://doi.org/10.1093/ageing/afr0149. Barrett-Connor E. The economic and human cost of osteoporotic fracture. Am J Med. 1995, 98:3S–8S. https://doi.org/10.1016/S0002-9343(05)80037-310. Anderasen TJ, Cole MG, Ciampi A, Belzile E et al. Persistent delirium in older hospital patients: a systematic review of frequency and prognosis. Age and Ageing 2009, 38:19–26. https://doi.org/10.1093/ageing/afn25311. FlikweertER, WendtKW, DiercksRL et al. Complications after hip fracture surgery: are they preventable? Eur J Trauma EmergSurg 2017, 1-8. https://doi.org/10.1007/s00068-017-0826-212. Rolfson D. The causes of delirium. (chapter 6) in: J. Lindesay, K. Rockwood (Eds.) Delirium in old age. Oxford University Press, 2002:101–22.13. Quereshy FA, Saxena S. and Lawley D. Deliruium in the elderly: A clinical review. Postgrad. Med. J. 2009, 85: 405–13. https://doi.org/10.1136/pgmj.2008.07202514. Sciard D, Cattano D, Hussain Met al. Perioperative management of proximal hip fractures in the elderly: the surgeon and the anesthesiologist. Minerva Anestesiol 2011;77: 715-722 https://www.minervamedica.it/en/journals/minerva-anestesiologica/article.php?cod=R02Y2011N07A0715015. Han L, McCusker J, Cole M et al. Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients. Arch. Intern. Med. 2001, 161: 1099–105. https://doi.org/10.1001/archinte.161.8.109916. Martins S. and Fernandes L. Delirium in elderly peole: a review. Frontiers in Neurology, 2012, 3:101 https://doi.org/10.3389/fneur.2012.0010117. Brauer C, Morrison RS, Silberzweig SB et al. The cause of delirium in patients with hip fracture. Arch-Intern. Med. 2000, 160, 1856–60. https://doi.org/10.1001/archinte.160.12.185618. Burns A, Gallagley A and Byrne J. Delirium. J. Neurol. Neurosurg. Psychiatr. 2004,75: 362–7. https://doi.org/10.1136/jnnp.2003.02336619. Cole, MG. Delirium in elderly patients. Am. J. Geriatr. Psychiatry 2004, 12:7–21. https://doi.org/10.1097/00019442-200401000-0000220. CCSMH. National Guidelines for Seniors Mental Health - The Assessment and Treatment of Delirium. Toronto: Canadian Coalition for Seniors Mental Health, 2006. https://ccsmh.ca/wp-content/uploads/2016/03/NatlGuideline_Delirium.pdf21. Inouye SK. Delirium in older persons. N. Engl. J. Med. 2006,354:1157–65. https://doi.org/10.1056/NEJMra05232122. Skrobik Y. Broadening our perspectives on ICU delirium risk factors. Crit Care 2009, 13:160. https://doi.org/10.1186/cc791723. Noimark D. Predicting the onset of delirium in the post-operative patient. Age Ageing 2009, 38:368–73 https://doi.org/10.1093/ageing/afp02424. Fong TG, Tulebaev SR, Inouye SK. Delirium in elderly adults: diagnosis, prevention and treatment. Nat Rev Neurol 2009, 5:210–20 https://doi.org/10.1038/nrneurol.2009.2425. Hshieh TT, Fong TG, Marcantonio ER et al. Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A BiolSci Med Sci 2008, 63:764–72. https://doi.org/10.1093/gerona/63.7.76426. Benowitz NL. Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics. Annu Rev PharmacolToxicol 2009, 49:57–71 https://doi.org/10.1146/annurev.pharmtox.48.113006.09474227. Hughes JR. Effects of abstinence from tobacco: valid symptoms and time course. Nicotine Tob Res 2007, 9:315–27. https://doi.org/10.1080/1462220070118891928. Papaioannou A, Fraidakis O, Michaloudis D et al. The impact of the type of anaesthesia on cognitive status and delirium during the first postoperative days in elderly patients. Eur J Anaesthesiol 2005, 22:492–99. https://doi.org/10.1017/S026502150500084029. S. Jean Hsieh, Mili Shum, Andrew N. Lee et al. Cigarette Smoking as a Risk Factor for Delirium in Hospitalized and Intensive Care Unit Patients. Ann Am ThoracSoc 2013, 10:496–503. https://doi.org/10.1513/AnnalsATS.201301-001OC30. Santos FS, Velasco IT, Fraguas R Jr. Risk factors for delirium in the elderly after coronary artery bypass graft surgery. IntPsychogeriatr 2004, 16:175–93. https://doi.org/10.1017/S104161020400036531. Bosmak FS, Gibim PT, Guimarães S et al. Incidence of delirium in postoperative patients treated with total knee and hip arthroplasty, Rev Assoc Med Bras 2017, 63(3):248-51 https://doi.org/10.1590/1806-9282.63.03.24832. Flacker JM, Cummings V, Mach JR Jr et al. The association of serum anticholinergic activity with delirium in elderly medical patients. Am J Geriatr Psychiatry 1998, 6:31–41. https://doi.org/10.1097/00019442-199802000-0000533. Foy A, O'Connell D, Henry D et al. Benzodiazepine use as a cause of cognitive impairment in elderly hospital inpatients. J Gerontol A BiolSci Med Sci 1995, 50:M99–106. https://doi.org/10.1093/gerona/50A.2.M9934. Gustafson Y, Berggren D, Brannstrom B et al. Acute confusional states in elderly patients treated for femoral neck fracture. J Am Geriatr Soc. 1988, 36(6): 525-30. DOI: 10.1111/j.1532-5415.1988.tb04023.x http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.1988.tb04023.x/full35. Pisani MA, Murphy TE, Araujo KL et al. Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med 2009, 37:177–83. https://doi.org/10.1097/CCM.0b013e318192fcf936. Schor JD, Levkoff SE, Lipsitz LA et al. Risk factors for delirium in hospitalized elderly. J Am Med Assoc 1992, 267:827–31. https://doi.org/10.1001/jama.1992.0348006007303337. Marcantonio ER, Juarez G, Goldman L et al. The relationship of postoperative delirium with psycho-active medications. JAMA 1994, 272:1518–22. https://doi.org/10.1001/jama.1994.0352019006403638. Dubois MJ, Bergeron N, Dumont M et al. Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 2001, 27:1297–304. https://doi.org/10.1007/s00134010101739. Litaker D, Locala J, Franco K et al. Preoperative risk factors for postoperative delirium. Gen Hosp Psychiatry 2001, 23:84–9. https://doi.org/10.1016/S0163-8343(01)00117-740. Clegg A, YoungJB. Which medications to avoid in people at risk of delirium: a systematic review. Age and Ageing 2011, 40:23–9. https://doi.org/10.1093/ageing/afq14041. Aldemir M, Özen S, Kara IH et al. Predisposing factors for delirium in the surgical intensive care unit. Critical Care 2001, 5:265-70 https://doi.org/10.1186/cc104442. Rodriguez RM, Corwin HL, Gettinger A et al. Nutritional deficiencies and blunted erythropoietin response as causes of the anemia of critical illness. J Crit Care 2001, 16:36–41. https://doi.org/10.1053/jcrc.2001.2179543. Gaskell H, Derry S, Andrew Moore R et al. Prevalence of anaemia in older persons: Systematic review. BMC Geriatr 2008, 8:1. https://doi.org/10.1186/1471-2318-8-144. Fleming RE, Bacon BR. Orchestration of iron homeostasis. N Engl J Med 2005, 352:1741–4. https://doi.org/10.1056/NEJMp04836345. Kramer AH and Zygun DA. Anemia and red blood cell transfusion in neurocritical care. Critical Care 2009, 13:R89 https://doi.org/10.1186/cc7916 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Facultatis Medicae Naissensis de Gruyter

Delirium Risk Factors in Elderly Patients Suffering from Femoral Neck Fractures

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© 2018 Ivana Milićević et al., published by De Gruyter Open
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Abstract

References1. Saxena S. and Lawley D. Delirium in the elderly: a clinical review. Postgrad. Med. J. 85, 2009; 405–13. https://doi.org/10.1136/pgmj.2008.0720252. Tucker GJ. The diagnosis of delirium and DSM-IV. Dement GeriatrCognDisord, 1999; 10:359-63. https://doi.org/10.1159/0000171713. Siddiqi N, House AO and Holmes JD. Occurrence and outcome of delirium in medical in-patients: a systematic literature review. Age Ageing 35, 2006; 350–64. https://doi.org/10.1093/ageing/afl0054. Theocharis Chr. Kyziridis. Post-operative delirium after hip fracture treatment: a review of the current literature, GMS Psycho-Social-Medicine 2006, 3: doc 01 http://www.egms.de/en/journals/psm/2006-3/psm000021.shtml5. Angela J, Bruce L, Craig W. Ritchie et al. The incidence of delirium associated with orthopedic surgery: a meta-analytic review. International Psycho-geriatrics 2007, 19: 197–214. https://doi.org/10.1017/S104161020600425X6. Ruggiero C, Bonamassa L, Pelini L et al. Early post-surgical cognitive dysfunction is a risk factor for mortality among hip fracture hospitalized older persons. OsteoporosInt 2017, 28:667–75. https://doi.org/10.1007/s00198-016-3784-37. Dubljanin Raspopovic E, MarkovicDenic L, Marinkovic Jet al. Early mortality after hip fracture: what matters? Psychogeriatrics 2014,15:95–101. https://doi.org/10.1111/psyg.12076Fliss8. Kat MG, de Jonghe JF, Vreeswijk Ret al. Mortality associated with delirium after hip-surgery: a 2-year follow-up study. Age and Ageing 2011, 40:312–18. https://doi.org/10.1093/ageing/afr0149. Barrett-Connor E. The economic and human cost of osteoporotic fracture. Am J Med. 1995, 98:3S–8S. https://doi.org/10.1016/S0002-9343(05)80037-310. Anderasen TJ, Cole MG, Ciampi A, Belzile E et al. Persistent delirium in older hospital patients: a systematic review of frequency and prognosis. Age and Ageing 2009, 38:19–26. https://doi.org/10.1093/ageing/afn25311. FlikweertER, WendtKW, DiercksRL et al. Complications after hip fracture surgery: are they preventable? Eur J Trauma EmergSurg 2017, 1-8. https://doi.org/10.1007/s00068-017-0826-212. Rolfson D. The causes of delirium. (chapter 6) in: J. Lindesay, K. Rockwood (Eds.) Delirium in old age. Oxford University Press, 2002:101–22.13. Quereshy FA, Saxena S. and Lawley D. Deliruium in the elderly: A clinical review. Postgrad. Med. J. 2009, 85: 405–13. https://doi.org/10.1136/pgmj.2008.07202514. Sciard D, Cattano D, Hussain Met al. Perioperative management of proximal hip fractures in the elderly: the surgeon and the anesthesiologist. Minerva Anestesiol 2011;77: 715-722 https://www.minervamedica.it/en/journals/minerva-anestesiologica/article.php?cod=R02Y2011N07A0715015. Han L, McCusker J, Cole M et al. Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients. Arch. Intern. Med. 2001, 161: 1099–105. https://doi.org/10.1001/archinte.161.8.109916. Martins S. and Fernandes L. Delirium in elderly peole: a review. Frontiers in Neurology, 2012, 3:101 https://doi.org/10.3389/fneur.2012.0010117. Brauer C, Morrison RS, Silberzweig SB et al. The cause of delirium in patients with hip fracture. Arch-Intern. Med. 2000, 160, 1856–60. https://doi.org/10.1001/archinte.160.12.185618. Burns A, Gallagley A and Byrne J. Delirium. J. Neurol. Neurosurg. Psychiatr. 2004,75: 362–7. https://doi.org/10.1136/jnnp.2003.02336619. Cole, MG. Delirium in elderly patients. Am. J. Geriatr. Psychiatry 2004, 12:7–21. https://doi.org/10.1097/00019442-200401000-0000220. CCSMH. National Guidelines for Seniors Mental Health - The Assessment and Treatment of Delirium. Toronto: Canadian Coalition for Seniors Mental Health, 2006. https://ccsmh.ca/wp-content/uploads/2016/03/NatlGuideline_Delirium.pdf21. Inouye SK. Delirium in older persons. N. Engl. J. Med. 2006,354:1157–65. https://doi.org/10.1056/NEJMra05232122. Skrobik Y. Broadening our perspectives on ICU delirium risk factors. Crit Care 2009, 13:160. https://doi.org/10.1186/cc791723. Noimark D. Predicting the onset of delirium in the post-operative patient. Age Ageing 2009, 38:368–73 https://doi.org/10.1093/ageing/afp02424. Fong TG, Tulebaev SR, Inouye SK. Delirium in elderly adults: diagnosis, prevention and treatment. Nat Rev Neurol 2009, 5:210–20 https://doi.org/10.1038/nrneurol.2009.2425. Hshieh TT, Fong TG, Marcantonio ER et al. Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A BiolSci Med Sci 2008, 63:764–72. https://doi.org/10.1093/gerona/63.7.76426. Benowitz NL. Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics. Annu Rev PharmacolToxicol 2009, 49:57–71 https://doi.org/10.1146/annurev.pharmtox.48.113006.09474227. Hughes JR. Effects of abstinence from tobacco: valid symptoms and time course. Nicotine Tob Res 2007, 9:315–27. https://doi.org/10.1080/1462220070118891928. Papaioannou A, Fraidakis O, Michaloudis D et al. The impact of the type of anaesthesia on cognitive status and delirium during the first postoperative days in elderly patients. Eur J Anaesthesiol 2005, 22:492–99. https://doi.org/10.1017/S026502150500084029. S. Jean Hsieh, Mili Shum, Andrew N. Lee et al. Cigarette Smoking as a Risk Factor for Delirium in Hospitalized and Intensive Care Unit Patients. Ann Am ThoracSoc 2013, 10:496–503. https://doi.org/10.1513/AnnalsATS.201301-001OC30. Santos FS, Velasco IT, Fraguas R Jr. Risk factors for delirium in the elderly after coronary artery bypass graft surgery. IntPsychogeriatr 2004, 16:175–93. https://doi.org/10.1017/S104161020400036531. Bosmak FS, Gibim PT, Guimarães S et al. Incidence of delirium in postoperative patients treated with total knee and hip arthroplasty, Rev Assoc Med Bras 2017, 63(3):248-51 https://doi.org/10.1590/1806-9282.63.03.24832. Flacker JM, Cummings V, Mach JR Jr et al. The association of serum anticholinergic activity with delirium in elderly medical patients. Am J Geriatr Psychiatry 1998, 6:31–41. https://doi.org/10.1097/00019442-199802000-0000533. Foy A, O'Connell D, Henry D et al. Benzodiazepine use as a cause of cognitive impairment in elderly hospital inpatients. J Gerontol A BiolSci Med Sci 1995, 50:M99–106. https://doi.org/10.1093/gerona/50A.2.M9934. Gustafson Y, Berggren D, Brannstrom B et al. Acute confusional states in elderly patients treated for femoral neck fracture. J Am Geriatr Soc. 1988, 36(6): 525-30. DOI: 10.1111/j.1532-5415.1988.tb04023.x http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.1988.tb04023.x/full35. Pisani MA, Murphy TE, Araujo KL et al. Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med 2009, 37:177–83. https://doi.org/10.1097/CCM.0b013e318192fcf936. Schor JD, Levkoff SE, Lipsitz LA et al. Risk factors for delirium in hospitalized elderly. J Am Med Assoc 1992, 267:827–31. https://doi.org/10.1001/jama.1992.0348006007303337. Marcantonio ER, Juarez G, Goldman L et al. The relationship of postoperative delirium with psycho-active medications. JAMA 1994, 272:1518–22. https://doi.org/10.1001/jama.1994.0352019006403638. Dubois MJ, Bergeron N, Dumont M et al. Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 2001, 27:1297–304. https://doi.org/10.1007/s00134010101739. Litaker D, Locala J, Franco K et al. Preoperative risk factors for postoperative delirium. Gen Hosp Psychiatry 2001, 23:84–9. https://doi.org/10.1016/S0163-8343(01)00117-740. Clegg A, YoungJB. Which medications to avoid in people at risk of delirium: a systematic review. Age and Ageing 2011, 40:23–9. https://doi.org/10.1093/ageing/afq14041. Aldemir M, Özen S, Kara IH et al. Predisposing factors for delirium in the surgical intensive care unit. Critical Care 2001, 5:265-70 https://doi.org/10.1186/cc104442. Rodriguez RM, Corwin HL, Gettinger A et al. Nutritional deficiencies and blunted erythropoietin response as causes of the anemia of critical illness. J Crit Care 2001, 16:36–41. https://doi.org/10.1053/jcrc.2001.2179543. Gaskell H, Derry S, Andrew Moore R et al. Prevalence of anaemia in older persons: Systematic review. BMC Geriatr 2008, 8:1. https://doi.org/10.1186/1471-2318-8-144. Fleming RE, Bacon BR. Orchestration of iron homeostasis. N Engl J Med 2005, 352:1741–4. https://doi.org/10.1056/NEJMp04836345. Kramer AH and Zygun DA. Anemia and red blood cell transfusion in neurocritical care. Critical Care 2009, 13:R89 https://doi.org/10.1186/cc7916

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Acta Facultatis Medicae Naissensisde Gruyter

Published: Mar 1, 2018

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