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Changes of Neopterin and Tryptophan in Serum and Cerebrospinal Fluid of Patients in Different Stages of HIV -1 Infection

Changes of Neopterin and Tryptophan in Serum and Cerebrospinal Fluid of Patients in Different... Moeller ('( al.: Tryp tophan and neopte rin in IlIV-\ infection Pte ridines Vol. 2, 1990, pp. 91 - 93 Short Communication , A. A. Moeller l), D. Fuchs11 G. Reibnegger 11 , M. Zaudig ll, E. R. Werner1) and H . Wachter 21 I) Max-Planck-Institut fur Psychiatrie, Kraepelinstr. 10, 0-8000 Mtinchen 10, Federal Republic of Germany 1) Institut fur Medizinische Chemie und Biochemie und Ludwig-Boltzmann Institut ftir AIDS Forschung, Universitat Innsbruck, A-6020 Innsbruck. Austria (Received Ma rch 1(90) Introduction Patients in the more advanced stages of human immunodeficiency virus (H IV)-l infection may develop a particular pattern of motor slowing, cognitive disturbances and minor neurological signs. The decline of cognitive functions is one of the main sou rces of morb idity in HIV-l infection because patients became disabled in their social function s and therefo re should be diagnosed as being demented according to the widely used Diagnos tic and Statistical Manual of M ental Disorders published by the American Psychiatric Association (1) . The so-called AIDS Demen tia Complex (ADC) was observed as initial clinical ma nifestation of HIV-l infection rarely detected even in patients wit h minor immunological abnormalities and preceding the occurrence of opportunistic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pteridines de Gruyter

Changes of Neopterin and Tryptophan in Serum and Cerebrospinal Fluid of Patients in Different Stages of HIV -1 Infection

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Publisher
de Gruyter
Copyright
Copyright © 1990 by the
ISSN
0933-4807
eISSN
2195-4720
DOI
10.1515/pteridines.1990.2.2.91
Publisher site
See Article on Publisher Site

Abstract

Moeller ('( al.: Tryp tophan and neopte rin in IlIV-\ infection Pte ridines Vol. 2, 1990, pp. 91 - 93 Short Communication , A. A. Moeller l), D. Fuchs11 G. Reibnegger 11 , M. Zaudig ll, E. R. Werner1) and H . Wachter 21 I) Max-Planck-Institut fur Psychiatrie, Kraepelinstr. 10, 0-8000 Mtinchen 10, Federal Republic of Germany 1) Institut fur Medizinische Chemie und Biochemie und Ludwig-Boltzmann Institut ftir AIDS Forschung, Universitat Innsbruck, A-6020 Innsbruck. Austria (Received Ma rch 1(90) Introduction Patients in the more advanced stages of human immunodeficiency virus (H IV)-l infection may develop a particular pattern of motor slowing, cognitive disturbances and minor neurological signs. The decline of cognitive functions is one of the main sou rces of morb idity in HIV-l infection because patients became disabled in their social function s and therefo re should be diagnosed as being demented according to the widely used Diagnos tic and Statistical Manual of M ental Disorders published by the American Psychiatric Association (1) . The so-called AIDS Demen tia Complex (ADC) was observed as initial clinical ma nifestation of HIV-l infection rarely detected even in patients wit h minor immunological abnormalities and preceding the occurrence of opportunistic

Journal

Pteridines – de Gruyter

Published: May 1, 1990

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