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An interactive tool for identifying patient subgroups based on arbitrary characteristics for medical research

An interactive tool for identifying patient subgroups based on arbitrary characteristics for... AbstractWe present an analysis tool for subgroup identification in medical research based on feature analysis. Our use case is intracranial aneurysms. In the tool, an aneurysm-of-interest’s most similar aneurysms within a database are found. Similarity is defined via user-selected parameters, which can be entirely arbitrary. Different interactive outputs and visualizations include a heatmap view and a graph, which give an intuitive feedback to support researchers in the consideration of research questions, which in the present use case often relate to rupture risk analysis. The tool was evaluated with a pilot study and phantom database and received favorable results for its requirements of reliability and appropriate and clear outputs. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Directions in Biomedical Engineering de Gruyter

An interactive tool for identifying patient subgroups based on arbitrary characteristics for medical research

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Publisher
de Gruyter
Copyright
© 2021 by Walter de Gruyter Berlin/Boston
eISSN
2364-5504
DOI
10.1515/cdbme-2021-1010
Publisher site
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Abstract

AbstractWe present an analysis tool for subgroup identification in medical research based on feature analysis. Our use case is intracranial aneurysms. In the tool, an aneurysm-of-interest’s most similar aneurysms within a database are found. Similarity is defined via user-selected parameters, which can be entirely arbitrary. Different interactive outputs and visualizations include a heatmap view and a graph, which give an intuitive feedback to support researchers in the consideration of research questions, which in the present use case often relate to rupture risk analysis. The tool was evaluated with a pilot study and phantom database and received favorable results for its requirements of reliability and appropriate and clear outputs.

Journal

Current Directions in Biomedical Engineering – de Gruyter

Published: Aug 1, 2021

Keywords: subgroup selection; feature analysis; intracranial aneurysms

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