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A Polarized Light Microscopy Study in a Case of Morphea

A Polarized Light Microscopy Study in a Case of Morphea AbstractWe report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ARS Medica Tomitana de Gruyter

A Polarized Light Microscopy Study in a Case of Morphea

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Publisher
de Gruyter
Copyright
© 2020 Mocanu Liliana et al., published by Sciendo
ISSN
1841-4036
eISSN
1841-4036
DOI
10.2478/arsm-2020-0001
Publisher site
See Article on Publisher Site

Abstract

AbstractWe report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis.

Journal

ARS Medica Tomitanade Gruyter

Published: Feb 1, 2020

Keywords: morphea; polarized microscopy; picro sirius red; collagen

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