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A new dimeric naphtho- γ -pyrone from an endophytic fungus Aspergillus niger AKRN associated with the roots of Entandrophragma congoënse collected in Cameroon

A new dimeric naphtho- γ -pyrone from an endophytic fungus Aspergillus niger AKRN associated with... Abstract A new dimeric naphtho- γ -pyrone, 2-hydroxydihydronigerone ( 1 ), along with five compounds, nigerone ( 2 ), pyrophen ( 3 ), kojic acid ( 4 ), 4-(hydroxymethyl)-5-hydroxy-2 H -pyran-2-one ( 5 ), and p -hydroxyphenylacetic acid ( 6 ), was isolated from an endophytic fungus Aspergillus niger AKRN associated with the roots of Entandrophragma congoënse . The structure of the new compound has been elucidated using spectroscopic data including 1D and 2D NMR as well as the high-resolution mass spectrometry. Compounds 1 – 5 showed weak antimicrobial activity on five selected Gram-negative bacteria, namely Enterobacter aerogenes (CM64), Enterobacter cloacae (BM67), Klebsiella pneumonia (K2), and Escherichia coli (ATCC8739 and ATCC10536). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Zeitschrift für Naturforschung B de Gruyter

A new dimeric naphtho- γ -pyrone from an endophytic fungus Aspergillus niger AKRN associated with the roots of Entandrophragma congoënse collected in Cameroon

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References (12)

Publisher
de Gruyter
Copyright
Copyright © 2015 by the
ISSN
0932-0776
eISSN
1865-7117
DOI
10.1515/znb-2015-0036
Publisher site
See Article on Publisher Site

Abstract

Abstract A new dimeric naphtho- γ -pyrone, 2-hydroxydihydronigerone ( 1 ), along with five compounds, nigerone ( 2 ), pyrophen ( 3 ), kojic acid ( 4 ), 4-(hydroxymethyl)-5-hydroxy-2 H -pyran-2-one ( 5 ), and p -hydroxyphenylacetic acid ( 6 ), was isolated from an endophytic fungus Aspergillus niger AKRN associated with the roots of Entandrophragma congoënse . The structure of the new compound has been elucidated using spectroscopic data including 1D and 2D NMR as well as the high-resolution mass spectrometry. Compounds 1 – 5 showed weak antimicrobial activity on five selected Gram-negative bacteria, namely Enterobacter aerogenes (CM64), Enterobacter cloacae (BM67), Klebsiella pneumonia (K2), and Escherichia coli (ATCC8739 and ATCC10536).

Journal

Zeitschrift für Naturforschung B – de Gruyter

Published: Sep 1, 2015

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