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PARP inhibitors need an extra STING for therapeutic efficacy

PARP inhibitors need an extra STING for therapeutic efficacy <jats:p>PARP inhibitors require the recruitment of CD8<jats:sup>+</jats:sup> T cells through STING-cGAS signaling to maximize tumor regression.</jats:p> http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Science Translational Medicine CrossRef

PARP inhibitors need an extra STING for therapeutic efficacy

Science Translational Medicine , Volume 11 (494): eaax9557 – May 29, 2019

PARP inhibitors need an extra STING for therapeutic efficacy


Abstract

<jats:p>PARP inhibitors require the recruitment of CD8<jats:sup>+</jats:sup> T cells through STING-cGAS signaling to maximize tumor regression.</jats:p>

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Publisher
CrossRef
ISSN
1946-6234
DOI
10.1126/scitranslmed.aax9557
Publisher site
See Article on Publisher Site

Abstract

<jats:p>PARP inhibitors require the recruitment of CD8<jats:sup>+</jats:sup> T cells through STING-cGAS signaling to maximize tumor regression.</jats:p>

Journal

Science Translational MedicineCrossRef

Published: May 29, 2019

There are no references for this article.