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Risk factors for post-operative delirium in elderly Chinese patients

Risk factors for post-operative delirium in elderly Chinese patients ObjectiveThe purpose of this study was to systematically analyze the risk factors for post-operative delirium (PD) in elderly patients in an effort to provide a basis for developing relevant clinical interventions in China.MethodsAll published studies focusing on the risk factors for PD among elderly patients in Wanfant Data, China National Knowledge Infrastructure (CNKI), and VIP were collected according to the inclusion and exclusion criteria of this study. A meta-analysis was performed on case-control studies using RevMan5.2 software, and the incidence of PD risk factors was calculated among case series.ResultsSixteen studies, including 8 case-control studies and 8 case series, were included in the current study. There were 353 cases and 2008 controls in the case-control studies. The pooled odds ratios (95% CI) of PD risk factors were as follows: hypoxemia, 2.58 (1.59~4.18); pulmonary infection, 4.51 (2.23∼9.13); hypertension, 2.16 (1.20∼3.89); coronary heart disease, 1.50 (0.82∼2.73); post-operative pain, 3.18 (1.63∼6.20); general anesthesia, 3.64 (0.94∼14.11); operative time, 1.70 (0.79∼3.66); and senility, 0.52 (−0.25∼1.29). The meta-analysis showed that hypoxemia, pulmonary infection, hypertension, coronary heart disease, post-operative pain, general anesthesia, operative time, and senility were significant risk factors for PD. There were 404 cases in the case series, and the incidence of hypoxemia, hypertension, general anesthesia, diabetes mellitus, senility, coronary heart disease, pulmonary infection, and cerebrovascular disease was 62.62%, 55.90%, 33.7%, 24.8%, 16.58%, 15.3%, 13.9%, and 12.1%, respectively, which was much higher than other risk factors.ConclusionSenility, hypertension, coronary heart disease, diabetes mellitus, pulmonary infection, hypoxemia, post-operative pain, and general anesthesia are significant risk factors for PD among elderly Chinese patients. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Family Medicine and Community Health British Medical Journal

Risk factors for post-operative delirium in elderly Chinese patients

Risk factors for post-operative delirium in elderly Chinese patients

Family Medicine and Community Health , Volume 2 (4) – Dec 1, 2014

Abstract

ObjectiveThe purpose of this study was to systematically analyze the risk factors for post-operative delirium (PD) in elderly patients in an effort to provide a basis for developing relevant clinical interventions in China.MethodsAll published studies focusing on the risk factors for PD among elderly patients in Wanfant Data, China National Knowledge Infrastructure (CNKI), and VIP were collected according to the inclusion and exclusion criteria of this study. A meta-analysis was performed on case-control studies using RevMan5.2 software, and the incidence of PD risk factors was calculated among case series.ResultsSixteen studies, including 8 case-control studies and 8 case series, were included in the current study. There were 353 cases and 2008 controls in the case-control studies. The pooled odds ratios (95% CI) of PD risk factors were as follows: hypoxemia, 2.58 (1.59~4.18); pulmonary infection, 4.51 (2.23∼9.13); hypertension, 2.16 (1.20∼3.89); coronary heart disease, 1.50 (0.82∼2.73); post-operative pain, 3.18 (1.63∼6.20); general anesthesia, 3.64 (0.94∼14.11); operative time, 1.70 (0.79∼3.66); and senility, 0.52 (−0.25∼1.29). The meta-analysis showed that hypoxemia, pulmonary infection, hypertension, coronary heart disease, post-operative pain, general anesthesia, operative time, and senility were significant risk factors for PD. There were 404 cases in the case series, and the incidence of hypoxemia, hypertension, general anesthesia, diabetes mellitus, senility, coronary heart disease, pulmonary infection, and cerebrovascular disease was 62.62%, 55.90%, 33.7%, 24.8%, 16.58%, 15.3%, 13.9%, and 12.1%, respectively, which was much higher than other risk factors.ConclusionSenility, hypertension, coronary heart disease, diabetes mellitus, pulmonary infection, hypoxemia, post-operative pain, and general anesthesia are significant risk factors for PD among elderly Chinese patients.

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References (27)

Publisher
British Medical Journal
Copyright
© 2014 Family Medicine and Community Health
ISSN
2305-6983
eISSN
2009-8774
DOI
10.15212/FMCH.2014.0119
Publisher site
See Article on Publisher Site

Abstract

ObjectiveThe purpose of this study was to systematically analyze the risk factors for post-operative delirium (PD) in elderly patients in an effort to provide a basis for developing relevant clinical interventions in China.MethodsAll published studies focusing on the risk factors for PD among elderly patients in Wanfant Data, China National Knowledge Infrastructure (CNKI), and VIP were collected according to the inclusion and exclusion criteria of this study. A meta-analysis was performed on case-control studies using RevMan5.2 software, and the incidence of PD risk factors was calculated among case series.ResultsSixteen studies, including 8 case-control studies and 8 case series, were included in the current study. There were 353 cases and 2008 controls in the case-control studies. The pooled odds ratios (95% CI) of PD risk factors were as follows: hypoxemia, 2.58 (1.59~4.18); pulmonary infection, 4.51 (2.23∼9.13); hypertension, 2.16 (1.20∼3.89); coronary heart disease, 1.50 (0.82∼2.73); post-operative pain, 3.18 (1.63∼6.20); general anesthesia, 3.64 (0.94∼14.11); operative time, 1.70 (0.79∼3.66); and senility, 0.52 (−0.25∼1.29). The meta-analysis showed that hypoxemia, pulmonary infection, hypertension, coronary heart disease, post-operative pain, general anesthesia, operative time, and senility were significant risk factors for PD. There were 404 cases in the case series, and the incidence of hypoxemia, hypertension, general anesthesia, diabetes mellitus, senility, coronary heart disease, pulmonary infection, and cerebrovascular disease was 62.62%, 55.90%, 33.7%, 24.8%, 16.58%, 15.3%, 13.9%, and 12.1%, respectively, which was much higher than other risk factors.ConclusionSenility, hypertension, coronary heart disease, diabetes mellitus, pulmonary infection, hypoxemia, post-operative pain, and general anesthesia are significant risk factors for PD among elderly Chinese patients.

Journal

Family Medicine and Community HealthBritish Medical Journal

Published: Dec 1, 2014

Keywords: Elderly patientPost-operative deliriumRisk factorSystematic reviewMeta-analysis

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