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26 Introduction to Special Issue on Bioinformatics Bioinformatics is heading towards a higher degree of automation, parallelism, and reliability in the collection, storage, and elaboration of biological or biologically-derived information. At present, the ever increasing number of sequenced genomes offers major opportunities and challenges at the level of functional biology for the establishment of a correlation between sequences and their functions in order to comprehend biological processes at the molecular level. Such crucial understanding has a big impact in many fields of the life sciences and would allow, for instance, for effectively engineering so-called "synthetic" living organisms. The main steps in this direction include the collection and integration of available data as well as the effective transfer of the information about the sequence functions to newly sequenced organisms. Moreover, increased knowledge of the gene function at the cellular level and improved approach formalization are needed to successfully design de novo biological systems on the basis of this information. Rather than solely relying on new software solutions, the combination of bioinformatics with micro and nanotechnologies will play a significant role in solving these challenges and further increasing biological knowledge. For instance, major improvements increasingly are expected from the next-generation
ACM Journal on Emerging Technologies in Computing Systems (JETC) – Association for Computing Machinery
Published: Nov 1, 2013
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