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Bradykinesia Recognition in Parkinson’s Disease via Single RGB Video

Bradykinesia Recognition in Parkinson’s Disease via Single RGB Video Parkinson’s disease is a progressive nervous system disorder afflicting millions of patients. Among its motor symptoms, bradykinesia is one of the cardinal manifestations. Experienced doctors are required for the clinical diagnosis of bradykinesia, but sometimes they also miss subtle changes, especially in early stages of such disease. Therefore, developing auxiliary diagnostic methods that can automatically detect bradykinesia has received more and more attention. In this article, we employ a two-stage framework for bradykinesia recognition based on the video of patient movement. First, convolution neural networks are trained to localize keypoints in each video frame. These time-varying coordinates form motion trajectories that represent the whole movement. From the trajectory, we then propose novel measurements, namely stability, completeness, and self-similarity, to quantify different motor behaviors. We also propose a periodic motion model called PMNet. An encoder--decoder structure is applied to learn a low dimensional representation of a motion process. The compressed motion process and quantified motor behaviors are combined as inputs to a fully-connected neural network. Different from the traditional means, our solution extends the application scenario outside the hospital and can be easily transplanted to conduct similar tasks. A commonly used clinical assessment is served as a case study. Experimental results based on real-world data validate the effectiveness of our approach for bradykinesia recognition. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ACM Transactions on Knowledge Discovery from Data (TKDD) Association for Computing Machinery

Bradykinesia Recognition in Parkinson’s Disease via Single RGB Video

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References (46)

Publisher
Association for Computing Machinery
Copyright
Copyright © 2020 ACM
ISSN
1556-4681
eISSN
1556-472X
DOI
10.1145/3369438
Publisher site
See Article on Publisher Site

Abstract

Parkinson’s disease is a progressive nervous system disorder afflicting millions of patients. Among its motor symptoms, bradykinesia is one of the cardinal manifestations. Experienced doctors are required for the clinical diagnosis of bradykinesia, but sometimes they also miss subtle changes, especially in early stages of such disease. Therefore, developing auxiliary diagnostic methods that can automatically detect bradykinesia has received more and more attention. In this article, we employ a two-stage framework for bradykinesia recognition based on the video of patient movement. First, convolution neural networks are trained to localize keypoints in each video frame. These time-varying coordinates form motion trajectories that represent the whole movement. From the trajectory, we then propose novel measurements, namely stability, completeness, and self-similarity, to quantify different motor behaviors. We also propose a periodic motion model called PMNet. An encoder--decoder structure is applied to learn a low dimensional representation of a motion process. The compressed motion process and quantified motor behaviors are combined as inputs to a fully-connected neural network. Different from the traditional means, our solution extends the application scenario outside the hospital and can be easily transplanted to conduct similar tasks. A commonly used clinical assessment is served as a case study. Experimental results based on real-world data validate the effectiveness of our approach for bradykinesia recognition.

Journal

ACM Transactions on Knowledge Discovery from Data (TKDD)Association for Computing Machinery

Published: Feb 10, 2020

Keywords: Bradykinesia

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