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The use of BeG vaccine in the prevention of tuberculosis has long been a controver sial and emotionally charged issue in the United States. Although available in this country, BeG vaccine has been used but little in the prevention of tuberculosis. In contrast, BeG vaccination has been the major thrust of the World Health Organiza tion's efforts to control tuberculosis in countries with high rates of transmission, and is credited with a major role in reducing tuberculosis morbidity. In controlling tuberculosis in the United States, reliance has been placed by public health authorities on early detection of new cases using the tuberculin skin test, prompt chemotherapy, and preventive isoniazid treatment of household contacts, skin-test converters, and other high-risk groups with positive skin tests. The validity of this approach has been evident, for tuberculosis has declined sharply in the United States during the past several decades. United States Public Health Service data (I, 2) indicate that in 1953 there were 84,000 new cases of tuberculosis and 19,700 deaths due to tuberculosis; in 1975 there were only 33,500 new cases, and the number of tuberculosis deaths had declined to 3,500. Other, more general factors, such as improved nutrition and the
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1977
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