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PAUL HENKIND, M.D., PH.D. Department of Ophthalmology, Albert Einstein College of Mcdicine Montefiorc Hospital and Medical Center, Bron.v, New York Macular deg eneration is a non sp c ci fi c term encomp assing diverse disor ders . Most common is senile macular degeneration (SMD), a major cause of visual i mp a irment in the elderly. In addition, there are several hereclo macular degenerations which affect indiv iduals in the first few decades of lif e (1), as well as cerebro-macular degenerations which rarely are limited to the macular region (2). Some of the latter may be due to "slow" virus infections, the best documented example being subacute sclerosing panence phalitis, which is caused by the measles virus (3). Maculopathies, both re versible and irreversible, secondary to medications such as the synthetic an timalarials (4, 5), topical e pineph r i n e (6), and allopurinol (7) have re cently beeIl recorded. Degelleration of the macula may also occur in con j unction with other ocular disease. Wise & \1\7ang v i va t (8) ha ve noted an exaggerated macular rcsponse in a number of retinal disorders. The most common feature of all forms of macular
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1971
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