Access the full text.
Sign up today, get DeepDyve free for 14 days.
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
M.D. AND CHARLES W. ISRAEL, M.D. Department of Ophthalmology, University of Miami School of Medicine, Miami, Florida Two major recent advances in late syphilis of interest to every clinician have occurred in the past decade. These are: 1. the frequency of clinically progressive late seronegative syphilis; and 2. the presence of treponemes in patients with late syphilis despite penicillin therapy. The presence of trepo nemes in lymph nodes, despite penicillin therapy for syphilis, was first re ported in both animals and man by Coliart in 1962 (1-3). This observation was confirmed in rabbits by Del Carpio Of greater interest to the ophthalmologist was the discovery of treponemes in human aqueous humor, after administration of large doses of penicillin (4), and in man by BOl1cinelli (5). (6). This discovery was thereafter confirmed by Goldman (7), Jo ne s (8), and Christman (9). Furthermore, study of a control group confirmed the absence of spirochetes in the aqueous humor of patients with senile cata racts, also examined by the same fluorescent antibody technique (10). Fi nally, the persistence of treponemes in the lymph nodes of both man and rabbit, despite treatment and even retreatment with penicillin, has been con firmed by
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1971
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.