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- Publisher
- Annual Reviews
- Copyright
- Copyright © 2009 by Annual Reviews. All rights reserved
- ISSN
- 0066-4219
- eISSN
- 1545-326X
- DOI
- 10.1146/annurev.med.60.061107.145152
- pmid
- 19630569
- Publisher site
- See Article on Publisher Site
Abstract
The genomic era has been characterized by an exponential increase in the number of targets in the management of breast cancer. Prognostic profiling has helped to determine which tumors are more likely to be associated with poor disease-free survival. Gene expression profiles are being studied in order to improve predictions of response and toxicity. Epigenetics is being evaluated for its ability to influence estrogen receptor expression. However, these fields require further validation. This review discusses the advances in the management of breast cancer through genomic evaluation.
Journal
Annual Review of Medicine – Annual Reviews
Published: Feb 18, 2009