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- Publisher
- Annual Reviews
- Copyright
- Copyright 1987 Annual Reviews. All rights reserved
- Subject
- Review Articles
- ISSN
- 0732-0582
- eISSN
- 1545-3278
- DOI
- 10.1146/annurev.iy.05.040187.003201
- pmid
- 2885016
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- See Article on Publisher Site
Abstract
This review describes the functional effects on lymphocytes of receptors for a wide variety of hormones and autacoids. Lymphocytes include T cells and B cells. The lineage of NK and K cells is unclear, but in this review we consider them lymphocytes. T cells are divided into subsets, including regulatory cells (helper T cells, suppressor T cells, contra suppressor T cells) and effector T cells (delayed hypersensitivity T cells and cytotoxic T cells-CTL). Cell surface glycoproteins separate mouse and human T cells into two broad subsets. Most mouse helper and delayed hypersensitivity T cells are L3T4 + Lyt 1 + Ly t 2 - Ly t 3-. Most mouse suppressor T cells and CTL are L3T4- Lyt 1- Lyt 2+ Lyt 3+. As defined by the nomenclature I Abbreviations: ADA, adenosine deaminase; ADCC, antibody-dependent cellular cyto toxicity; CTL, cytotoxic T lymphocyte; E-rosette, rosettes between sheep erythrocytes and human T cells; GIF, glycosylation inhibitory factor; HI and H2, histamine-type I and -type 2 receptor; HCSF, histamine cell stimulatory factor (stimulates histamine synthesis); HSF, histamine in d uced suppressor factor; 5-HT, 5-hydroxytryptamine; IBMX, iso - butylmethylxanthine, an antagonist of adenosine R; and R. receptors; IP3, inositol- 1 .4.5triphosphate; K, killer
Journal
Annual Review of Immunology – Annual Reviews
Published: Apr 1, 1987