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Infectious Disease: Bacterial

Infectious Disease: Bacterial The field of bacterial infection in the past two years can be characterized more by the problems it has presented than by.the progress which has been made. We seem to be in a lull after the period of turbulence which marked the first saturation of our population with antibiotiCs. No antibacterial drugs of exceptional and unique 'properties were developed and no great advances in the treatment of infection occurred. Diseases of greatest interest were those caused by staphylococci and Gram-negative bacilli, organisms which, under normal conditions, are benign inhabitants of the skin and mucous mem­ branes of man,· but which either naturally possess, or soon acquire, anti­ microbial resistance. The infections caused by these organisms, their fre­ quency, epidemic tendencies, pathogenesis, treatment, and explanations for their current prevalence, are the principal problems which are described in this review. We have formed the opinion that these problem infections are not going to be effectively controlled by presently available antimicrobial therapy, and that their alleviation must probably await the discovery of new approaches to treatment. Some encouragement for such developments may be found in several new concepts of infection and its treatment included in the following review. STAPHYLOCOCCAL DISEASE Apprehension http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Medicine Annual Reviews

Infectious Disease: Bacterial

Annual Review of Medicine , Volume 11 (1) – Feb 1, 1960

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Publisher
Annual Reviews
Copyright
Copyright 1960 Annual Reviews. All rights reserved
Subject
Review Articles
ISSN
0066-4219
eISSN
1545-326X
DOI
10.1146/annurev.me.11.020160.000315
pmid
14410130
Publisher site
See Article on Publisher Site

Abstract

The field of bacterial infection in the past two years can be characterized more by the problems it has presented than by.the progress which has been made. We seem to be in a lull after the period of turbulence which marked the first saturation of our population with antibiotiCs. No antibacterial drugs of exceptional and unique 'properties were developed and no great advances in the treatment of infection occurred. Diseases of greatest interest were those caused by staphylococci and Gram-negative bacilli, organisms which, under normal conditions, are benign inhabitants of the skin and mucous mem­ branes of man,· but which either naturally possess, or soon acquire, anti­ microbial resistance. The infections caused by these organisms, their fre­ quency, epidemic tendencies, pathogenesis, treatment, and explanations for their current prevalence, are the principal problems which are described in this review. We have formed the opinion that these problem infections are not going to be effectively controlled by presently available antimicrobial therapy, and that their alleviation must probably await the discovery of new approaches to treatment. Some encouragement for such developments may be found in several new concepts of infection and its treatment included in the following review. STAPHYLOCOCCAL DISEASE Apprehension

Journal

Annual Review of MedicineAnnual Reviews

Published: Feb 1, 1960

There are no references for this article.