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J. O'Brien, S. Day, W. Burnham (1986)
CONTROLLED TRIAL OF SMALL BIPOLAR PROBE IN BLEEDING PEPTIC ULCERSThe Lancet, 327
D. Barer, A. Ogilvie, D. Henry, M. Dronfield, D. Coggon, S. French, S. Ellis, M. Atkinson, M. Langman (1983)
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.The New England journal of medicine, 308 26
N. Soehendra, H. Grimm, M. Stenzel (1985)
Injection of Nonvariceal Bleeding Lesions of the Upper Gastrointestinal TractEndoscopy, 17
P. Wara, A. Højsgaard, E. Amdrup (1980)
Endoscopic Electrocoagulation - An Alternative to Operative Hemostasis in Active Gastroduodenal Bleeding?Endoscopy, 12
G. Krejs, K. Little, H. Westergaard, J. Hamilton, D. Spady, D. Polter (1987)
Laser photocoagulation for the treatment of acute peptic-ulcer bleeding. A randomized controlled clinical trial.The New England journal of medicine, 316 26
F. Silverstein, David Gilbert, F. Tedesco, N. Buenger, J. Persing (1981)
The national ASGE survey on upper gastrointestinal bleeding. II. Clinical prognostic factors.Gastrointestinal endoscopy, 27 2
Several methods of endoscopically controlling acute, nonvariceal upper. gastrointestinal bleeding have been developed. Some, such as the laser, heater probe, and bipolar electrocoagulation, have been evaluated in con trolled clinical trials. The purpose of this paper is to discuss endoscopic control of nonvariceal gastroduodenal hemorrhage and to consider whether improvement in outcome is likely with any of these devices. Techniques and results of controlled clinical trials are reviewed. INTRODUCTION Acute upper gastrointestinal (GI) bleeding is a common and serious emerg ency. The mortality rate has remained at about 10% over the past 40 years, despite improvements in intensive care, blood product replacement, endoscopy, and surgical techniques. Some progress has occurred because mortality rates do not reflect the steady age increase of patients with GI bleeding-the average age is about 60 years, and about 25% of patients are over 75 years (1). A large American Society of Gastrointestinal Endoscopists (ASGE) survey on acute upper GI bleeding enumerated several patient charac teristics associated with this clinical condition (2). Duodenal or gastric ulcers accounted for 45% of cases. In the majority of patients, bleeding stopped, did not recur, and mortality was low. In about 25%, however, bleeding was continuous and mortality
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1987
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