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CARDIOVASCULAR DISEASE: ARTERIAL HYPERTENSION";.! By MAURICE SOKOLOW, M.D. AND PAUL J. SANAZARO, M.D.3 Department of Medicine and Cardiovascular Research Institute, University of California School of Medicine San Francisco, California The , of HT: proof of effective drug control of severe HT and recognition of two major causes of "curable" HT-renal artery lesions and aldosteronism. While numerous clinical, epidemiological, and experimental observations have illuminated various facets of the field, they have produced more spec ulations than direct answers to questions of etiology and patliogenesis. Restrictions of space limit this review to a brief survey of significant trends. Pickering's (1) book is a masterful presentation of the subject, empha sizing particularly the physiological and conceptual aspects. A study of 114 hypertensive patients relating personality to various physiologic parameters, including details of frequent interviews in 26 cases, is presented by Wolf and co-authors (2). The symposium of the WeIlcome Foundation on Hypotensive Drugs (3) covers the pharmacologic aspects and clinical applications of hypotensive drugs and control of vascular tone. Smirk's excellent book (4) emphasizes the pathogenesis of the disease and the specific details and effectiveness of therapeutic agents. A sound clinical dis cussion of HT disease by Hoobler (5) will be
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1960
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