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The survey of literature pertaining to this review was completed in July, 305 DRIPPS comparable groups (age, sex, physical status, type, and severity of operation) with nitrous-oxide, oxygen, and ether on the one hand and nitrous-oxide, oxygen, and curare on the other.2 In such a study, in addition to an analysis of death rate, careful records should be made of all three phases of anesthesia, induction, maintenance, and recovery. During induction, for example, the incidence of excitement, anoxia, laryngospasm, reduction of blood pressure and of pulse pressure might be listed. During maintenance one could record such data as the difficulties of pulmonary ventilation, problems associated with positive pressure inflation of the lungs, and the response of the circula tion to surgical manipulations. During recovery one would be interested in the incidence of nausea, vomiting, headache, urinary retention, intestinal distention, time of ambulation, and adequacy of wound healing. A large series of patients with a variety of preoperative conditions must be included. In such a way, one might be able to determine the price paid by patients who did or did not receive curare drugs. Although such a comprehensive study is not available, many potential dangers of the curare
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1954
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