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The Immunologic Complexity of Growing Up with Malaria—Is Scientific Understanding Coming of Age?

The Immunologic Complexity of Growing Up with Malaria—Is Scientific Understanding Coming of Age? In the current issue of Clinical and Vaccine Immunology, Mandala et al. report changes in lymphocyte populations in children with uncomplicated malaria, severe malarial anemia, and cerebral malaria compared to controls (W. L. Mandala et al., Clin Vaccine Immunol 23:95–103, 2016, http://dx.doi.org/10.1128/CVI.00564-15). This commentary discusses the importance of understanding both helpful and detrimental aspects of the antimalarial immune response that are critical to malaria vaccine development and considers how these responses may relate to antimalarial vaccine safety and efficacy. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical and Vaccine Immunology American Society For Microbiology

The Immunologic Complexity of Growing Up with Malaria—Is Scientific Understanding Coming of Age?

Clinical and Vaccine Immunology , Volume 23 (2) – Feb 1, 2016

The Immunologic Complexity of Growing Up with Malaria—Is Scientific Understanding Coming of Age?

Clinical and Vaccine Immunology , Volume 23 (2) – Feb 1, 2016

Abstract

In the current issue of Clinical and Vaccine Immunology, Mandala et al. report changes in lymphocyte populations in children with uncomplicated malaria, severe malarial anemia, and cerebral malaria compared to controls (W. L. Mandala et al., Clin Vaccine Immunol 23:95–103, 2016, http://dx.doi.org/10.1128/CVI.00564-15). This commentary discusses the importance of understanding both helpful and detrimental aspects of the antimalarial immune response that are critical to malaria vaccine development and considers how these responses may relate to antimalarial vaccine safety and efficacy.

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References (34)

Publisher
American Society For Microbiology
Copyright
Copyright © 2016, American Society for Microbiology. All Rights Reserved.
ISSN
1556-6811
eISSN
1556-679X
DOI
10.1128/CVI.00697-15
pmid
26677199
Publisher site
See Article on Publisher Site

Abstract

In the current issue of Clinical and Vaccine Immunology, Mandala et al. report changes in lymphocyte populations in children with uncomplicated malaria, severe malarial anemia, and cerebral malaria compared to controls (W. L. Mandala et al., Clin Vaccine Immunol 23:95–103, 2016, http://dx.doi.org/10.1128/CVI.00564-15). This commentary discusses the importance of understanding both helpful and detrimental aspects of the antimalarial immune response that are critical to malaria vaccine development and considers how these responses may relate to antimalarial vaccine safety and efficacy.

Journal

Clinical and Vaccine ImmunologyAmerican Society For Microbiology

Published: Feb 1, 2016

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